Shedding light on antisocial behavior through genetically informed research
Antisocial behavior (ASB) refers to a set of behaviors that violate social norms and disregard
the well-being and rights of others. In this review, we synthesize evidence from studies using …
the well-being and rights of others. In this review, we synthesize evidence from studies using …
[HTML][HTML] Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes
Attention-deficit/hyperactivity disorder (ADHD) co-occurs with many other psychiatric
disorders and traits. In this review, we summarize and interpret the existing literature on the …
disorders and traits. In this review, we summarize and interpret the existing literature on the …
Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis
JJ Tielbeek, E Uffelmann, BS Williams… - Molecular …, 2022 - nature.com
Despite the substantial heritability of antisocial behavior (ASB), specific genetic variants
robustly associated with the trait have not been identified. The present study by the Broad …
robustly associated with the trait have not been identified. The present study by the Broad …
Shared genetics and causality underlying epilepsy and attention-deficit hyperactivity disorder
Y Wu, Y Li, J Zhu, J Long - Psychiatry research, 2022 - Elsevier
The prevalence of attention deficit hyperactivity disorder (ADHD) in patients with epilepsy
was much higher than prevalence in general population, and vice versa. The mechanisms …
was much higher than prevalence in general population, and vice versa. The mechanisms …
[HTML][HTML] Examining the biological mechanisms of human mental disorders resulting from gene-environment interdependence using novel functional genomic …
PP Silveira, MJ Meaney - Neurobiology of Disease, 2023 - Elsevier
We explore how functional genomics approaches that integrate datasets from human and
non-human model systems can improve our understanding of the effect of gene …
non-human model systems can improve our understanding of the effect of gene …
Insights into attention-deficit/hyperactivity disorder from recent genetic studies
Attention-deficit/hyperactivity disorder (ADHD) is a common and highly heritable
neurodevelopmental disorder (NDD). In this narrative review, we summarize recent …
neurodevelopmental disorder (NDD). In this narrative review, we summarize recent …
Integrative multi‐omics analysis of genomic, epigenomic, and metabolomics data leads to new insights for Attention‐Deficit/Hyperactivity Disorder
N Hubers, FA Hagenbeek, R Pool… - American Journal of …, 2024 - Wiley Online Library
The evolving field of multi‐omics combines data and provides methods for simultaneous
analysis across several omics levels. Here, we integrated genomics (transmitted and non …
analysis across several omics levels. Here, we integrated genomics (transmitted and non …
Neurogenetic mechanisms of risk for ADHD: Examining associations of polygenic scores and brain volumes in a population cohort
Background ADHD polygenic scores (PGSs) have been previously shown to predict ADHD
outcomes in several studies. However, ADHD PGSs are typically correlated with ADHD but …
outcomes in several studies. However, ADHD PGSs are typically correlated with ADHD but …
Generalized genetic liability to substance use disorders
Lifetime and temporal co-occurrence of substance use disorders (SUDs) is common and
compared with individual SUDs is characterized by greater severity, additional psychiatric …
compared with individual SUDs is characterized by greater severity, additional psychiatric …
Genetics of child aggression, a systematic review
Excessive and persistent aggressiveness is the most common behavioral problem that leads
to psychiatric referrals among children. While half of the variance in childhood aggression is …
to psychiatric referrals among children. While half of the variance in childhood aggression is …