Innate immunity includes a cellular and a humoral arm. PTX3 is a fluid-phase pattern
recognition molecule conserved in evolution which acts as a key component of humoral …

The innate immune system comprises a cellular and a humoral arm. Humoral pattern
recognition molecules include complement components, collectins, ficolins, and pentraxins …

Abstract Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity,
involved in resistance to selected pathogens and in the regulation of inflammation,–. The …

Abstract Pentraxin-3 (PTX3) belongs to the pentraxine family, innate immune regulators
involved in angiogenesis, proliferation and immune escape in cancer. Here, we evaluated …

Activation of nuclear factor κB (NF-κB) induces mesenchymal (MES) transdifferentiation and
radioresistance in glioma stem cells (GSCs), but molecular mechanisms for NF-κB activation …

The pentraxin is a superfamily of proteins with the same domain known as the pentraxin
domain at C-terminal. This family has two subgroups, namely; short pentraxins (C-reactive …

Cutaneous melanoma is one of the most aggressive cancers characterized by a high
plasticity, a propensity for metastasis, and drug resistance. Melanomas are composed of …

Components of the cellular and the humoral arm of the immune system are essential
elements of the tumour microenvironment (TME). The TME includes tumour‐associated …

Since its discovery in 1992, long pentraxin 3 (PTX3) has been characterized as soluble
patter recognition receptor, a key player of the innate immunity arm with non-redundant …

Extracellular vesicles (EVs) act as carriers of molecular and oncogenic signatures present in
subsets of tumour cells and tumour-associated stroma, and as mediators of intercellular …