Ca2+-release channels are giant membrane proteins that control the release of Ca2+ from
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …

The fatality of cancer is mainly bestowed to the property of otherwise benign tumor cells to
become malignant and invade surrounding tissues by circumventing normal tissue barriers …

Calgranulin C (S100A12) is a member of the S100 family of proteins that undergoes a
conformational change upon calcium binding allowing them to interact with target molecules …

The S100 proteins are exclusively expressed in vertebrates and are the largest subgroup
within the superfamily of EF-hand Ca 2+-binding proteins Generally, S100 proteins are …

Safe and effective gene therapy approaches require targeted tissue-specific transfer of a
therapeutic transgene. Besides traditional approaches, such as transcriptional and …

S100A1, a small homodimeric EF-hand Ca2+-binding protein (~ 21 kDa), plays an important
regulatory role in Ca2+ signaling pathways involved in various biological functions including …

In heart and skeletal muscle an S100 protein family member, S100A1, binds to the
ryanodine receptor (RyR) and promotes Ca 2+ release. Using competition binding assays …

S100A1, a 21-kDa dimeric Ca 2+-binding protein, is an enhancer of cardiac Ca 2+ release
and contractility and a potential therapeutic agent for the treatment of cardiomyopathy. The …

S100A12 is expressed at sites of acute, chronic, and allergic inflammation. S100 proteins
have regions of high sequence homology, but the" hinge" region between the conserved …

Antral follicle size is a useful predictive marker of the competency of enclosed oocytes for
yielding an embryo following in vitro maturation and fertilization. However, the molecular …