The novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes major
challenges to the healthcare system. SARS-CoV-2 infection leads to millions of deaths …

Individuals with sickle cell disease (SCD) and sickle cell trait (SCT) have many risk factors
that could make them more susceptible to COVID-19 critical illness and death compared to …

Patients with sickle cell disease (SCD) are at high risk of developing serious infections,
therefore, understanding the impact that severe acute respiratory syndrome coronavirus 2 …

The transfusion of red blood cells (RBCs) is a crucial treatment for sickle cell disease (SCD).
While often beneficial, the frequent use of transfusions is associated with numerous …

This systematic review aimed to provide an overview of the clinical profile and outcome of
COVID-19 infection in patients with hemoglobinopathy. The rate of COVID-19 mortality and …

Importance Sickle cell trait (SCT), defined as the presence of 1 hemoglobin beta sickle allele
(rs334-T) and 1 normal beta allele, is prevalent in millions of people in the US, particularly in …

We surveyed published papers and an international sickle cell disease (SCD) registry to
detect susceptibility and clinical course of coronavirus disease 2019 (COVID‐19) in SCD …

Background Most studies that explore the long-term effects of COVID-19 are based on
subjectively reported symptoms, while laboratory-measured biomarkers are mainly …

Background Clinical manifestations and severity of SARS-CoV-2 infection in individuals with
sickle cell disease (SCD) and sickle cell trait (SCT) are not well understood yet. Methods We …

It is highly expected that COVID-19 infection will have devastating consequences in sickle
cell disease (SCD) patients due to endothelial activation and decreased tissue and organ …