Spontaneous dog osteoarthritis—a One Medicine vision

RL Meeson, RJ Todhunter, G Blunn, G Nuki… - Nature Reviews …, 2019 - nature.com
Osteoarthritis (OA) is a global disease that, despite extensive research, has limited treatment
options. Pet dogs share both an environment and lifestyle attributes with their owners, and a …

Etiopathogenesis of canine cruciate ligament disease: a scoping review

GW Niebauer, B Restucci - Animals, 2023 - mdpi.com
Simple Summary The spontaneous rupture of the cranial cruciate ligament in the stifle joints
of dogs is one of the most common veterinary orthopedic problems. Largely unknown …

Use of a bioactive scaffold to stimulate anterior cruciate ligament healing also minimizes posttraumatic osteoarthritis after surgery

MM Murray, BC Fleming - The American journal of sports …, 2013 - journals.sagepub.com
Background: Although anterior cruciate ligament (ACL) reconstruction is the treatment gold
standard for ACL injury, it does not reduce the risk of posttraumatic osteoarthritis. Therefore …

Radiographic risk factors for contralateral rupture in dogs with unilateral cranial cruciate ligament rupture

C Chuang, MA Ramaker, S Kaur, RA Csomos… - PloS one, 2014 - journals.plos.org
Background Complete cranial cruciate ligament rupture (CR) is a common cause of pelvic
limb lameness in dogs. Dogs with unilateral CR often develop contralateral CR over time …

Genome-wide association analysis in dogs implicates 99 loci as risk variants for anterior cruciate ligament rupture

LA Baker, B Kirkpatrick, GJM Rosa, D Gianola… - PLoS …, 2017 - journals.plos.org
Anterior cruciate ligament (ACL) rupture is a common condition that can be devastating and
life changing, particularly in young adults. A non-contact mechanism is typical. Second ACL …

Extended long‐term radiographic and functional comparison of tibial plateau leveling osteotomy vs tibial tuberosity advancement for cranial cruciate ligament rupture …

EV Moore, R Weeren, M Paek - Veterinary Surgery, 2020 - Wiley Online Library
Objective To report extended long‐term outcomes of dogs with cranial cruciate ligament
rupture treated by tibial plateau leveling osteotomy (TPLO) or tibial tuberosity advancement …

Femorotibial kinematics in dogs with cranial cruciate ligament insufficiency: a three-dimensional in-vivo fluoroscopic analysis during walking

S Tinga, SE Kim, SA Banks, SC Jones, BH Park… - BMC veterinary …, 2018 - Springer
Abstract Background Cranial cruciate ligament (CrCL) insufficiency is a degenerative
condition that is a common cause of pelvic limb lameness and osteoarthritis in dogs …

Autologous bone marrow-derived mesenchymal stem cells modulate molecular markers of inflammation in dogs with cruciate ligament rupture

P Muir, EC Hans, M Racette, N Volstad, SJ Sample… - PLoS …, 2016 - journals.plos.org
Mid-substance rupture of the canine cranial cruciate ligament rupture (CR) and associated
stifle osteoarthritis (OA) is an important veterinary health problem. CR causes stifle joint …

Correlates of estimated lifetime cruciate ligament survival inform potential rupture risk reduction strategies: findings from the Exceptional Aging in Rottweilers Study

DJ Waters, R Fu, AE Carrillo, EC Chiang, AH Maras… - Scientific Reports, 2023 - nature.com
Cranial cruciate ligament (CCL) rupture is one of the most commonly diagnosed orthopedic
conditions of pet dogs, making estimated lifetime cruciate ligament survival an attractive …

Arthroscopic assessment of stifle synovitis in dogs with cranial cruciate ligament rupture

JP Little, JA Bleedorn, BJ Sutherland, R Sullivan… - PloS one, 2014 - journals.plos.org
Cranial cruciate ligament rupture (CR) is a degenerative condition in dogs that typically has
a non-contact mechanism. Subsequent contralateral rupture often develops in dogs with …