DNA has played an early and powerful role in the development of bottom-up
nanotechnologies, not least because of DNA's precise, predictable, and controllable …

The intriguing structural diversity in folded topologies available to guanine-rich nucleic acid
repeat sequences have made four-stranded G-quadruplex structures the focus of both basic …

Over the past decade, nucleic acid chemists have seen the spectacular emergence of
molecules designed to interact efficiently and selectively with a peculiar DNA structure …

The telomeric G-rich single-stranded DNA can adopt in vitro an intramolecular quadruplex
structure, which has been shown to directly inhibit telomerase activity. The reactivation of …

Potassium is especially crucial in modulating the activity of muscles and nerves whose cells
have specialized ion channels for transporting potassium. Normal body function extremely …

G-quadruplexes are guanine-rich nucleic acids that fold by forming successive quartets of
guanines (the G-tetrads), stabilized by intra-quartet hydrogen bonds, inter-quartet stacking …

The i-motif structure is formed in cytosine-rich sequences, its building block being the
cytosine· cytosine+ base pair. This structure is particularly stable at pH values below …

Pyrene-functionalized oligonucleotides (PFOs) are increasingly explored as tools in
fundamental research, diagnostics and nanotechnology. Their popularity is linked to the …

Living cells contain a variety of biomolecules including nucleic acids, proteins,
polysaccharides, and metabolites as well as other soluble and insoluble components. These …

i-Motif DNA structures have previously been utilised for many different nanotechnological
applications, but all have used acidic conditions to fold the DNA. Herein we describe the use …