Maintenance of epithelial tissues needs the stroma. When the epithelium changes, the
stroma inevitably follows. In cancer, changes in the stroma drive invasion and metastasis …

Cell migration is a process which is essential during embryonic development, throughout
adult life and in some pathological conditions. Cadherins, and more specifically the neural …

Tumours recruit mesenchymal stem cells to facilitate healing, which induces their conversion
into cancer-associated fibroblasts that facilitate metastasis. However, this process is poorly …

Purpose: Cell adhesion molecules are of crucial importance in cancer invasion and
metastasis. Epithelial to mesenchymal transition, characterized by reduced E-cadherin and …

SIP1/ZEB2 is a member of the δEF-1 family of two-handed zinc finger nuclear factors. The
expression of these transcription factors is associated with epithelial mesenchymal …

Epithelial-mesenchymal transition (EMT) involving down-regulation of E-cadherin is thought
to play a fundamental role during early steps of invasion and metastasis of carcinoma cells …

Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …

The intracellular signaling events causing tumor cells to become metastatic are not well
understood. N-cadherin and FGF-2 synergistically increase migration, invasion, and …

PURPOSE:: This is part 1 of a 2-part review. Research into the molecular mechanisms
underlying the various aspects of prostate cancer (PCa) requires the use of in vivo and in …

Invasion causes cancer malignancy. We review recent data about cellular and molecular
mechanisms of invasion, focusing on cross-talk between the invaders and the host. Cancer …