Recent developments in the chemistry and biological applications of benzoxaboroles

A Adamczyk-Wozniak, KM Borys… - Chemical …, 2015 - ACS Publications
1. INTRODUCTION Benzoxaboroles, first obtained by Torssell in 1957, 1 remained
underestimated for a long time. The new beginning for these remarkable compounds took …

The unique chemistry of benzoxaboroles: current and emerging applications in biotechnology and therapeutic treatments

CT Liu, JW Tomsho, SJ Benkovic - Bioorganic & medicinal chemistry, 2014 - Elsevier
Benzoxaboroles have garnered much attention in recent years due to their diverse
applications in bio-sensing technology, material science, and therapeutic intervention. Part …

Design, synthesis, and structure–activity relationship of 7-propanamide benzoxaboroles as potent anticancer agents

J Zhang, J Zhang, G Hao, W Xin, F Yang… - Journal of Medicinal …, 2019 - ACS Publications
Benzoxaboroles, as a novel class of bioactive molecules with unique physicochemical
properties, have been shown to possess excellent antimicrobial activities with tavaborole …

Synthesis and cytotoxicity of Baylis-Hillman template derived betulinic acid-triazole conjugates

P Suman, A Patel, L Solano, G Jampana, ZS Gardner… - Tetrahedron, 2017 - Elsevier
Several alkynes and azides were prepared starting from betulinic acid and Baylis-Hillman
reaction-derived allylic alcohols. These alkynes and azides were then coupled under click …

Benzoxaboroles: New emerging and versatile scaffold with a plethora of pharmacological activities

B Dhawan, G Akhter, H Hamid, P Kesharwani… - Journal of Molecular …, 2022 - Elsevier
Benzoxaboroles are versatile boron heterocyclic compounds that have demonstrated a
plethora of pharmacological activities including anti-fungal, anti-inflammatory, anti-malarial …

Recent developments in the synthesis of bioactive boron-containing compounds

L Ji, H Zhou - Tetrahedron Letters, 2021 - Elsevier
Boron-containing compounds which possess unique and attractive properties have recently
received increasing attention in organic, material and medicinal chemistry. Specifically, they …

The synthesis of benzoxaboroles and their applications in medicinal chemistry

J Zhang, MY Zhu, YN Lin, HC Zhou - Science China Chemistry, 2013 - Springer
Benzoxaborole, as a versatile scaffold, plays important roles in organic synthesis, molecular
recognition and supramolecular chemistry. It is also a privileged structure in medicinal …

Chalcone–benzoxaborole hybrids as novel anticancer agents

J Zhang, F Yang, Z Qiao, M Zhu, H Zhou - Bioorganic & medicinal …, 2016 - Elsevier
In this study, we report the synthesis of a series of chalcone–benzoxaborole hybrid
molecules and the evaluation of their anticancer activity. Their anticancer potency and …

Synthesis and evaluation of functionalized aminobenzoboroxoles as potential anti-cancer agents

P Suman, BP Patel, AV Kasibotla, LN Solano… - Journal of …, 2015 - Elsevier
Several aminobenzoboroxole derivatives have been prepared starting from o-
boronobenzaldehyde employing reductive amination protocol. The corresponding …

Synthesis and evaluation of functionalized benzoboroxoles as potential anti-tuberculosis agents

MA Alam, K Arora, S Gurrapu, SK Jonnalagadda… - Tetrahedron, 2016 - Elsevier
Several derivatives of aminobenzoboroxole have been prepared starting from 2-
boronobenzaldehyde. All of these derivatives have been evaluated for their anti …