Host-and pathogen-specific factors interplay with the environment in a complex fashion to
determine the outcome of infection with Mycobacterium tuberculosis (Mtb), resulting in one …

Molecular typing has revolutionized epidemiological studies of infectious diseases,
including those of a mycobacterial etiology. With the advent of fingerprinting techniques …

Cough is a predominant feature of respiratory infection and, in tuberculosis, is of prime
importance for transmitting infection. Tuberculosis is transmitted by the air, yet the process …

Mechanisms underlying variability in transmission of Mycobacterium tuberculosis strains
remain undefined. By characterizing high and low transmission strains of M. tuberculosis in …

The transmission of tuberculosis is complex. Necessary factors include a source case with
respiratory disease that has developed sufficiently for Mycobacterium tuberculosis to be …

Experimental animal models of tuberculosis (TB) have convincingly demonstrated that
inhaled dose predicts immunopathology and survival. In contrast, the importance of inhaled …

Tuberculosis claims more human lives than any other infectious disease. This alarming
epidemic has fuelled the development of novel antimicrobials and diagnostics. However …

NTCA Guidelines for Respiratory Isolation and Restrictions to Reduce Transmission of
Pulmonary Tuberculosis in Community Settings NTCA Guidelines for Respiratory Isolation and …

Globally, the prevalence of tuberculosis (TB) disease is higher in males. This study
examined the effect of sex and age on Mycobacterium tuberculosis (Mtb) infection …

The goal of this study was to identify individuals at risk of progression and reactivation
among household contacts (HHC) of pulmonary TB cases in Vitoria, Brazil. We first …