The neuroimmune system–where aging and excess alcohol intersect

ER Carlson, SP Guerin, K Nixon, LK Fonken - Alcohol, 2023 - Elsevier
As the percentage of the global population over age 65 grows, and with it a subpopulation of
individuals with alcohol use disorder (AUD), understanding the effect of alcohol on the aged …

Age modifies the effect of ethanol on behavior: Investigations in adolescent, adult and aged rats

DB Matthews, BM Imhoff - International Review of Neurobiology, 2021 - Elsevier
The number of older people is increasing in most if not all countries in the world. In addition,
the amount of alcohol consumption in the aged population is increasing and the …

Elevated customary alcohol consumption attenuates opioid effects

MM Cherrier, DD Shen, L Shireman, AJ Saxon… - Pharmacology …, 2021 - Elsevier
Background Regular alcohol consumption is on the rise among older adults and has the
potential of altering the subjective experience of pain and response to pain medications …

A comparison of hippocampal microglial responses in aged and young rodents following dependent and non-dependent binge drinking

IR Grifasi, WA Evans, AD Rexha, LW Sako… - International review of …, 2019 - Elsevier
Alcoholism is a highly visible and prevalent issue in the United States. Although binge-
drinking is assumed to be a college-age problem, older adults (ages 65+) consume binge …

Acute ethanol administration produces larger spatial and nonspatial memory impairments in 29–33 month old rats compared to adult and 18–24 month old rats

DB Matthews, S Scaletty, A Schreiber… - … Biochemistry and Behavior, 2020 - Elsevier
The average age of the population in many countries is continuing to increase. Older people
continue to consume alcohol, often in a binge like fashion. Previous research has …

Applying geriatric principles to hazardous drinking in older adults

MB Rodin - Clinics in Geriatric Medicine, 2022 - geriatric.theclinics.com
For many older adults, alcohol is an adjunct to family celebrations and other social
engagement that is important to their sense of well-being. 1, 2 Recently a respected …

Differential expression of presynaptic Munc13-1 and Munc13-2 in mouse hippocampus following ethanol drinking

A Ghosh, S Muthuraju, S Badal, J Wooden, JL Leasure… - Neuroscience, 2022 - Elsevier
The Munc13 family of proteins is critically involved in synaptic vesicle priming and release in
glutamatergic neurons in the brain. Munc13-1 binds to alcohol and, in Drosophila …

Preface: Setting the stage for understanding alcohol effects in late aging: A special issue including both human and rodent studies

T Deak, LM Savage - International review of neurobiology, 2019 - Elsevier
It is widely recognized that people worldwide are living longer than in previous decades,
with formidable projections regarding the expansion of elderly age groups in the decades to …