In nature, the self-assembly of sequence-specific biopolymers into hierarchical structures plays an essential role in the construction of functional biomaterials. To develop synthetic …
V Marti-Centelles, MD Pandey, MI Burguete… - Chemical …, 2015 - ACS Publications
Macrocyclic structures are common synthetic targets in drug discovery,(1, 2) and therefore, interest in their study is continuously increasing in this field.(3, 4) A classic example is …
Polymers with precisely defined monomeric sequences present an exquisite tool for controlling material properties by harnessing both the robustness of synthetic polymers and …
Bioinspired polymeric materials are attracting increasing attention due to significant advantages over their natural counterparts: the ability to precisely tune their structures over a …
R Jwad, D Weissberger, L Hunter - Chemical Reviews, 2020 - ACS Publications
Cyclic peptides are promising scaffolds for drug development, attributable in part to their increased conformational order compared to linear peptides. However, when optimizing the …
In most general terms, polymers and their supramolecular assemblies have been defining life on this planet since its conception. Polymers of nucleic acids carry the code of life and …
In the last decade, the field of sequence‐defined polymers and related ultraprecise, monodisperse synthetic macromolecules has grown exponentially. In the early stage, mainly …
The purpose of this paper is to introduce and highlight a few classes of traditional antimicrobial peptides with a focus on structure-activity relationship studies. After first …
M Szostak, J Aube - Chemical reviews, 2013 - ACS Publications
The amide bond is one of the most important functional groups in chemistry and biology. 1 Due to the strong resonance interaction between nN and π* C O orbitals (Figure 1), 2 the …