Genetic alteration is the driving force for thyroid tumorigenesis and progression, based upon
which novel approaches to the management of thyroid cancer can be developed. A recent …

Thyroid cancer is one of the few malignancies that are increasing in incidence. Recent
advances have improved our understanding of its pathogenesis; these include the …

Background: Anaplastic thyroid carcinomas (ATCs) are among the most lethal malignancies,
for which there is no effective treatment. Objective: In the present study, we aimed to …

Poorly differentiated (PD) thyroid carcinomas lie both morphologically and behaviorally
between well-differentiated and undifferentiated (anaplastic) carcinomas. Following the …

Papillary carcinoma is the most common type of thyroid malignancy. It has been recently
shown that these tumors commonly have one of three genetic alterations: BRAF point …

Anaplastic thyroid cancer (ATC) is a rare malignancy. While external beam radiation therapy
has improved locoregional control, the median survival of∼ 4 months has not changed in …

The oncogene BRAF V600E is the most frequent genetic event in papillary thyroid
carcinoma (PTC) but its prognostic impact still remains to be elucidated. We evaluated a …

Context: Because very few studies have examined the correlation between BRAF mutations
and clinicopathological features of papillary thyroid carcinoma (PTC), we analyzed here a …

Some cancer types are strongly associated with chronic inflammatory or infectious diseases
whereas others are not, but an inflammatory component is present in most human neoplastic …

Context: The clinicopathological characteristics and the molecular features of the follicular
variant of papillary thyroid carcinoma (FVPTC) remain controversial. Objective/Design …