Emerging ethical challenges raised by the evolution of vascularized composite allotransplantation

AL Caplan, B Parent, J Kahn, W Dean… - …, 2019 - journals.lww.com
Background. Despite early skepticism, the field of vascularized composite
allotransplantation (VCA) has demonstrated feasibility. The ethics of VCA have moved past …

Lessons learned from the first 15 years of penile transplantation and updates to the Baltimore Criteria

CD Lopez, AO Girard, IV Lake, BC Oh… - Nature Reviews …, 2023 - nature.com
Since 2006, five penis transplants have been performed worldwide. Mixed outcomes have
been reported, and two of the five penile transplants have required explantation. However …

Supercooling: a promising technique for prolonged preservation in solid organ transplantation, and early perspectives in vascularized composite allografts

Y Berkane, J Hayau, I Filz von Reiterdank… - Frontiers in …, 2023 - frontiersin.org
Ex vivo preservation of transplanted organs is undergoing spectacular advances. Machine
perfusion is now used in common practice for abdominal and thoracic organ transportation …

Total penis, scrotum, and lower abdominal wall transplantation

RJ Redett III, JW Etra, G Brandacher… - … England Journal of …, 2019 - Mass Medical Soc
Total Penis, Scrotum, and Lower Abdominal Wall Transplantation This letter describes
transplantation of the penis, scrotum, and lower abdominal wall in an injured veteran who …

[HTML][HTML] Masculinizing and defeminizing gender-affirming surgery

TC van de Grift - Best Practice & Research Clinical Obstetrics & …, 2023 - Elsevier
Transmasculine transgender and gender diverse individuals may request gender-affirming
surgery, standalone or in addition to other interventions. The choices and preferred …

Applied bioengineering in tissue reconstruction, replacement, and regeneration

JM Colazo, BC Evans, AF Farinas… - … Engineering Part B …, 2019 - liebertpub.com
To this day, tissue reconstruction and replacement to address extensive tissue defects due
to trauma, tumor resection, genetic and/or chronic diseases, or excessive debridement …

Graft vasculopathy of vascularized composite allografts in humans: a literature review and retrospective study

ZY Ng, AG Lellouch, IA Rosales… - Transplant …, 2019 - Wiley Online Library
Mechanisms of chronic rejection of vascularized composite allografts (VCA) remain poorly
understood and likely present along a spectrum of highly varied clinicopathological findings …

Large animal models of vascularized composite allotransplantation: a review of immune strategies to improve allograft outcomes

AJ Matar, RL Crepeau, GS Mundinger… - Frontiers in …, 2021 - frontiersin.org
Over the past twenty years, significant technical strides have been made in the area of
vascularized composite tissue allotransplantation (VCA). As in solid organ transplantation …

The Baltimore Criteria for an ethical approach to penile transplantation: a clinical guideline

LM Ngaage, A Elegbede, J Sugarman… - Transplant …, 2020 - Wiley Online Library
Significant advances and increasing acceptance of vascularized composite
allotransplantation (VCA) have contributed to emerging success of penile transplantation …

Vascularized composite allotransplantation: alternatives and catch-22s

JR Diaz-Siso, ZM Borab, NM Plana… - Plastic and …, 2018 - journals.lww.com
Technical success has been achieved in several forms of vascularized composite
allotransplantation, including hand, face, penis, and lower extremity. However, the risks of …