Bacterial adhesion to collagens: implications for biofilm formation and disease progression in the oral cavity

S Álvarez, C Leiva-Sabadini, CMAP Schuh… - Critical reviews in …, 2022 - Taylor & Francis
Collagen is the most abundant structural protein in the body and the main component of the
extracellular matrix of most tissues, including dentine and periodontal tissues. Despite the …

Methylglyoxal-dependent glycative stress is prevented by the natural antioxidant oleuropein in human dental pulp stem cells through Nrf2/Glo1 pathway

S Delle Monache, F Pulcini, R Frosini, V Mattei… - Antioxidants, 2021 - mdpi.com
Methylglyoxal (MG) is a potent precursor of glycative stress (abnormal accumulation of
advanced glycation end products, AGEs), a relevant condition underpinning the etiology of …

The Roles of Periodontal Bacteria in Atherosclerosis

X Huang, M Xie, X Lu, F Mei, W Song, Y Liu… - International Journal of …, 2023 - mdpi.com
Atherosclerosis (AS) is an inflammatory vascular disease that constitutes a major underlying
cause of cardiovascular diseases (CVD) and stroke. Infection is a contributing risk factor for …

Protective effects of Clostridium butyricum against oxidative stress induced by food processing and lipid-derived aldehydes in Caco-2 cells

J Li, H Shen, Z Zhao, D Cao, M Zeng, H Cai… - Applied Microbiology …, 2020 - Springer
The human body is almost always facing the oxidative stress caused by foodborne
aldehydes such as glyoxal (GO) and methylglyoxal (MGO), 4-hydroxyhexenal (HHE), and 4 …

Microfabrication-based engineering of biomimetic dentin-like constructs to simulate dental aging

S Álvarez, J Morales, P Tiozzo-Lyon, P Berrios… - Lab on a Chip, 2024 - pubs.rsc.org
Human dentin is a highly organized dental tissue displaying a complex microarchitecture
consisting of micrometer-sized tubules encased in a mineralized type-I collagen matrix. As …

Nanomechanical and molecular characterization of aging in dentinal collagen

CMAP Schuh, C Leiva-Sabadini… - Journal of Dental …, 2022 - journals.sagepub.com
Methylglyoxal (MGO) is an important molecule derived from glucose metabolism with the
capacity of attaching to collagen and generating advanced glycation end products (AGEs) …

Persistence of Tannerella forsythia and Fusobacterium nucleatum in Dental Plaque: a Strategic Alliance

A Sharma - Current oral health reports, 2020 - Springer
Abstract Purpose of Review The Gram-negative oral pathogen Tannerella forsythia is
implicated in the pathogenesis of periodontitis, an inflammatory disease characterized by …

Glycated collagen stimulates differentiation of gingival myofibroblasts

IN Retamal, R Hernández, F Melo… - Journal of …, 2017 - Wiley Online Library
Background: Glucose‐derived metabolites may alter the structure and biologic properties of
important proteins in periodontium, such as collagens. As a consequence, it is possible that …

Tannerella forsythia‐produced methylglyoxal causes accumulation of advanced glycation endproducts to trigger cytokine secretion in human monocytes

RP Settem, K Honma, M Shankar, M Li… - Molecular Oral …, 2018 - Wiley Online Library
The periodontal pathogen Tannerella forsythia has the unique ability to produce
methylglyoxal (MGO), an electrophilic compound which can covalently modify amino acid …

Enhancement of a Collagen Membrane for Bone Regeneration

BA Godoy-Galvez - 2023 - search.proquest.com
Abstract Guided Bone Regeneration (GBR) is a technique used to restore deficiencies in
bone architecture that have resulted from disease, loss of function or trauma. It involves …