Background Telomerase is a ribonucleoprotein complex consisting of a catalytic component
telomerase reverse transcriptase (TERT), internal RNA template and other co‐factors, and …

Background Comprehensive molecular studies on tumours are needed to delineate
immortalization process steps and identify sensitive prognostic biomarkers in thyroid cancer …

Telomeres are tandem repeats of DNA sequences protecting the end of linear
chromosomes. Replicative senescence due to telomere attrition is considered a tumor …

Background Thyroid nodules are commonly faced by clinicians as palpable nodules or
incidentally identified on imaging. Nodules that are found to be suspicious by imaging can …

There are concerns regarding overtreatment in papillary thyroid carcinoma (PTC). BRAF
V600E and TERT promoter mutations play important roles in the development of PTC …

DGCR8 emerged recently as miRNAs biogenesis pathway protein with a highlighted role in
thyroid disease. This study aimed to characterize this miRNA biogenesis component, in …

Solute carrier family 26 member 9 (SLC26A9) is a member of the Slc26a family of
multifunctional anion transporters that functions as a Cl-channel in parietal cells during acid …

The TERT gene encodes the reverse transcriptase subunit of telomerase and is normally
transcriptionally suppressed in differentiated human cells but reactivated in cancers where …

Simple Summary Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Serine
Protease 2 (TMPRSS2), and Furin are highly expressed in the normal thyroid gland. The …

Aims Upregulation of the telomerase reverse transcriptase (TERT) gene is a frequent finding
in follicular thyroid carcinomas (FTCs) with metastatic features. The augmented expression …