Apoptosis has long been recognized as a mechanism that kills the cancer cells by cytotoxic
drugs. In recent years, studies have proved that pyroptosis can also shrink tumors and inhibit …

Pyroptosis, a form of programmed cell death, has garnered increasing attention as it relates
to innate immunity and diseases. The discovery of caspase-1/3/4/5/8/11 function in sensing …

Neuroinflammation is considered as a detrimental factor in neurodegenerative diseases,
including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) …

Programmed Cell Death (PCD) is considered to be a pathological form of cell death when
mediated by an intracellular program and it balances cell death with survival of normal cells …

Cellular inflammasome activation causes caspase-1 cleavage of the pore-forming protein
gasdermin D (GSDMD) with subsequent pyroptotic cell death and cytokine release. Here …

Pyroptosis, a lytic pro-inflammatory type of programmed cell death, has been widely studied
in diverse inflammatory disease models. Membrane perforation and cell swelling induced by …

Increasing evidence has been reported regarding phytochemicals, plant secondary
metabolites, having therapeutic functions against numerous human diseases. Recently …

Pediatric cancers are the driving cause of death for children and adolescents. Due to safety
requirements and considerations, treatment strategies and drugs for pediatric cancers have …

Dioscin has gained immense popularity as a natural, bioactive steroid saponin, which offers
numerous medical benefits. The growing global incidence of disease‐associated morbidity …

Simple Summary Anticancer therapeutic approaches based solely on apoptosis induction
are often unsuccessful due to the activation of resistance mechanisms. The identification …