The application of polyhydroxyalkanoates as tissue engineering materials

GQ Chen, Q Wu - Biomaterials, 2005 - Elsevier
Polyhydoxyalkanoates (PHA) are polyesters produced by microorganisms under
unbalanced growth conditions. They are generally biodegradable and thermoprocessable …

Polyhydroxyalkanoates: the natural biopolyester for future medical innovations

ZW Ren, ZY Wang, YW Ding, JW Dao, HR Li… - Biomaterials …, 2023 - pubs.rsc.org
Polyhydroxyalkanoates (PHAs) are a family of natural microbial biopolyesters with the same
basic chemical structure and diverse side chain groups. Based on their excellent …

Biomedical applications of environmental friendly poly-hydroxyalkanoates

S Ansari, N Sami, D Yasin, N Ahmad… - International Journal of …, 2021 - Elsevier
Biological polyesters of hydroxyacids are known as polyhydroxyalkanoates (PHA). They
have proved to be an alternative, environmentally friendly and attractive candidate for the …

Medical application of microbial biopolyesters polyhydroxyalkanoates

Q Wu, Y Wang, GQ Chen - Artificial Cells, Blood Substitutes, and …, 2009 - Taylor & Francis
Polyhydroxyalkanoates (PHA) are a family of polyesters synthesized by microorganisms
under unbalanced growth conditions. PHA including poly-3-hydroxybutyrate (PHB) …

Scaffolds for bone restoration from cuttlefish

JHG Rocha, AF Lemos, S Agathopoulos, P Valério… - Bone, 2005 - Elsevier
Scaffolds of pure hydroxyapatite suitable for either direct clinical use or tissue-engineering
applications were successfully produced via hydrothermal transformation of aragonite …

Bacterial cellulose-modified polyhydroxyalkanoates scaffolds promotes bone formation in critical size calvarial defects in mice

A Codreanu, C Balta, H Herman, C Cotoraci, CV Mihali… - Materials, 2020 - mdpi.com
Bone regeneration is a claim challenge in addressing bone defects with large tissue deficits,
that involves bone grafts to support the activity. In vitro biocompatibility of the bacterial …

Comprehensive in vitro testing of calcium phosphate-based bioceramics with orthopedic and dentistry applications

R Albulescu, AC Popa, AM Enciu, L Albulescu… - Materials, 2019 - mdpi.com
Recently, a large spectrum of biomaterials emerged, with emphasis on various pure,
blended, or doped calcium phosphates (CaPs). Although basic cytocompatibility testing …

DNA aptamer immobilized hydroxyapatite for enhancing angiogenesis and bone regeneration

J Son, J Kim, K Lee, J Hwang, Y Choi, Y Seo, H Jeon… - Acta Biomaterialia, 2019 - Elsevier
In this study, we developed aptamer-conjugated hydroxyapatite (Apt-HA) that promotes
bone regeneration and angiogenesis. The 3R02 bivalent aptamer specific to vascular …

Hydrothermal growth of hydroxyapatite scaffolds from aragonitic cuttlefish bones

JHG Rocha, AF Lemos, S Agathopoulos… - … Research Part A: An …, 2006 - Wiley Online Library
Scaffolds of AB‐type carbonated hydroxyapatite (HA) were successfully produced via
hydrothermal transformation (HT) of aragonitic cuttlefish bones at 200° C. The transformation …

Medical applications of biopolyesters polyhydroxyalkanoates

G Chen, Y Wang - Chinese Journal of Polymer Science, 2013 - Springer
Microbial polyhydroxyalkanoates (PHAs) are a family of biopolyesters produced by many
wild type and engineered bacteria. PHAs have diverse structures accompanied by flexible …