Primary biliary cholangitis is a chronic, seropositive and female-predominant inflammatory
and cholestatic liver disease, which has a variable rate of progression towards biliary …

Primary biliary cirrhosis (PBC) is an autoimmune disease characterized by clinical
homogeneity among patients, an overwhelming female predominance, production of a …

Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …

Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by
autoimmune destruction of small to medium size intrahepatic bile ducts. The etiology of PBC …

The liver is the largest organ in the body and is generally regarded by non-immunologists as
not having lymphoid function. However, such is far from accurate. This review highlights the …

Dysregulated expression of long noncoding RNAs has been reported in many types of
cancers, indicating that it may play a critical role in tumorigenesis. The long noncoding RNA …

Cholestatic liver disorders are caused by genetic defects, mechanical aberrations, toxins, or
dysregulations in the immune system that damage the bile ducts and cause accumulation of …

BACKGROUND & AIMS: Primary biliary cirrhosis (PBC) is believed to result from the
interaction of genetic and environmental factors. The controlled studies aiming to assess risk …

Primary biliary cholangitis (PBC) causes chronic and persistent cholestasis in the liver,
eventually resulting in cirrhosis and hepatic failure without appropriate treatment. PBC …

The most difficult issue in autoimmunity remains etiology. Although data exist on effector
mechanisms in many autoimmune diseases, the underlying cause or causes are still …