[HTML][HTML] Endometriosis-associated infertility: From pathophysiology to tailored treatment

G Bonavina, HS Taylor - Frontiers in endocrinology, 2022 - frontiersin.org
Despite the clinically recognized association between endometriosis and infertility, the
mechanisms implicated in endometriosis-associated infertility are not fully understood …

Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis?

RM Marquardt, TH Kim, JH Shin, JW Jeong - International journal of …, 2019 - mdpi.com
In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …

Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

Physiologic events of embryo implantation and decidualization in human and non-human primates

MA Ochoa-Bernal, AT Fazleabas - International journal of molecular …, 2020 - mdpi.com
Reproduction is a fundamental process for the preservation of the human species. This
process requires a sequence of orchestrated events that are necessary for a successful …

Immune mechanisms at the maternal-fetal interface: perspectives and challenges

M PrabhuDas, E Bonney, K Caron, S Dey… - Nature …, 2015 - nature.com
Immune mechanisms at the maternal-fetal interface: perspectives and challenges | Nature
Immunology Skip to main content Thank you for visiting nature.com. You are using a browser …

[HTML][HTML] Endometrial receptivity in the eutopic endometrium of women with endometriosis: it is affected, and let me show you why

BA Lessey, JJ Kim - Fertility and sterility, 2017 - Elsevier
The endometrium maintains complex controls on proliferation and apoptosis as part of
repetitive menstrual cycles that prepare the endometrium for the window of implantation and …

Molecular signaling regulating endometrium–blastocyst crosstalk

M Massimiani, V Lacconi, F La Civita, C Ticconi… - International journal of …, 2019 - mdpi.com
Implantation of the embryo into the uterine endometrium is one of the most finely-regulated
processes that leads to the establishment of a successful pregnancy. A plethora of factors …

[HTML][HTML] Implications of immune dysfunction on endometriosis associated infertility

JE Miller, SH Ahn, SP Monsanto, K Khalaj, M Koti… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Endometriosis is a complex, inflammatory disease that affects 6-10% of reproductive-aged
women. Almost half of the women with endometriosis experience infertility. Despite the …

[HTML][HTML] Immune-inflammation gene signatures in endometriosis patients

SH Ahn, K Khalaj, SL Young, BA Lessey, M Koti… - Fertility and sterility, 2016 - Elsevier
Objective To determine if the molecular profiles of endometriotic lesions contain informative
measures of inflammation and immune dysfunction that may contribute to better …

Progesterone resistance in endometriosis: an acquired property?

B McKinnon, M Mueller, G Montgomery - Trends in Endocrinology & …, 2018 - cell.com
Endometriosis is the growth of endometrial tissue outside the uterus and is characterized by
progesterone resistance and changes in global and progesterone target gene expression …