The therapeutic properties of plants have been recognised since time immemorial. Many
pathological conditions have been treated using plant-derived medicines. These medicines …

Small-molecule drug discovery can be viewed as a challenging multidimensional problem in
which various characteristics of compounds—including efficacy, pharmacokinetics and …

Emerging threats to human health require a concerted effort in search of both preventive and
treatment strategies, placing natural products at the center of efforts to obtain new therapies …

Technological advances in high-throughput screening methods, combinatorial chemistry
and the design of virtual libraries have evolved in the pursuit of challenging drug targets …

Ubiquitous healthcare is the service that offers health-related information and contents to
users without any limitations of time and space. Especially, to offer customized services to …

Systems chemical biology, the integration of chemistry, biology and computation to generate
understanding about the way small molecules affect biological systems as a whole, as well …

Highlights•Scientific competency questions define current needs for data integration.•Top-
ranked questions aim for compound–target relations.•Open PHACTS enables semantic …

Spinal cord injury (SCI) research is a data-rich field that aims to identify the biological
mechanisms resulting in loss of function and mobility after SCI, as well as develop therapies …

Background The advent of high-throughput experimentation in biochemistry has led to the
generation of vast amounts of chemical data, necessitating the development of novel …

Following the elucidation of the human genome, chemogenomics emerged in the beginning
of the twenty-first century as an interdisciplinary research field with the aim to accelerate …