Digital health interventions refer to the use of digital technology and connected devices to
improve health outcomes and healthcare delivery. This includes telemedicine, electronic …

Large contact surfaces of protein–protein interactions (PPIs) remain to be an ongoing issue
in the discovery and design of small molecule modulators. Peptides are intrinsically capable …

An increase in the occurrence of viral infectious diseases is a global concern for human
health. According to a WHO report, dengue virus (DENV) is one of the most common viral …

The recent pandemic of severe acute respiratory syndrome–coronavirus2 (SARS-CoV-2)
infection (COVID-19) has put the world on serious alert. The main protease of SARS-CoV-2 …

Abstract The application of Artificial Intelligence (AI) to screen drug molecules with potential
therapeutic effects has revolutionized the drug discovery process, with significantly lower …

World Health Organization declared coronavirus disease (COVID-19) caused by SARS
coronavirus-2 (SARS-CoV-2) as pandemic. Its outbreak started in China in Dec 2019 and …

Chagas disease (CD) is a neglected disease that is endemic to Central and South America
and is caused by the protozoan parasite Trypanosoma cruzi. The discovery of new drugs …

Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2) emerged at the end
of 2019, causing a highly infectious and pathogenic disease known as 2019 coronavirus …

Hypertrophic cardiomyopathy (HCM) is characterized by unexplained left ventricular
hypertrophy (LVH) and is one of the major causes of sudden cardiac death (SCD). An exon …

Functionally important amino acid sequences in proteins are often located at multiple sites.
Three-dimensional structural analysis and site-directed mutagenesis may be performed to …