Neuroblastomas are tumours of sympathetic origin, with a heterogeneous clinical course
ranging from localized or spontaneously regressing to widely metastatic disease …

Approximately half of the patients diagnosed with neuroblastoma are classified as having
high-risk disease. This group continues to have inadequate cure rates despite multiagent …

Simple Summary Neuroblastoma is one of the most diffuse and the deadliest cancer in
children. While many advances have been made in the last few decades to improve patients' …

Neuroblastoma is the most common extracranial pediatric tumor and often presents with
metastatic disease, and patients with high-risk neuroblastoma have survival rates of~ 50 …

Neuroblastoma is the most common extra‐cranial solid tumor in children and is known for its
clinical heterogeneity. A greater understanding of the biology of this disease has led to both …

Purpose A pediatric normal tissue effects in the clinic (PENTEC) comprehensive review of
patients with childhood cancer who received radiation therapy (RT) to the liver was …

Cancer cells rewire their metabolism to promote cell proliferation, invasion, and metastasis.
Alterations in the lactate pathway have been characterized in diverse cancers, correlate with …

Background Neuroblastoma (NB) is considered an immunologically cold tumor and is
usually less responsive to immune checkpoint blockade (ICB). Tumor-associated …

Objective Radiotherapy (RT) is an integral part of the interdisciplinary treatment of patients
with high-risk neuroblastoma (NB). With the continuous improvements of outcome, the …

Background Tumor boards are part of standard care of patients with complex cancers, but
appropriate multidisciplinary expertise and infrastructure are often not available in low‐and …