Abstract Chitinase 3-like protein 1 (CHI3L1) participates in physiological and
pathophysiological process, such as cell survival, cell proliferation, tissue remodeling …

YKL-39 belongs to the evolutionarily conserved family of Glyco_18-containing proteins
composed of chitinases and chitinase-like proteins. Chitinase-like proteins (CLPs) are …

Background Natural killer (NK) cells require a functional lytic granule machinery to mediate
effective antitumor responses. Evading the lytic cargo deployed at the immune synapse (IS) …

MicroRNAs (miRNAs) have a crucial role in the regulation of gene expression in tumor
development, invasion, and metastasis. Herein, miRNA-340 (miR-340) has been shown to …

Thyroid cancer's incidence has increased by leaps and bounds over the last years and
accounts for 2.8% of new cases of cancers. This increasing bar is partially assisted by …

Abstract Background Chitinase-3-like protein-1 (CHI3L1), also known as human cartilage
glycoprotein-39 (HC-gp39), plays a role in several biological processes, including oxidative …

Approval of checkpoint inhibitors for treatment of metastatic triple negative breast cancer
(mTNBC) has opened the door for the use of immunotherapies against this disease …

Abstract Mammary Gland Protein-40 (MGP-40), also known as chitinase-3-like protein 1
(CHI3L1), is involved in critical biological processes such as inflammation, tissue …

Background Compared to minimally invasive brain metastases (MI BrM), highly invasive (HI)
lesions form abundant contacts with cells in the peritumoral brain parenchyma and are …

Introduction Chitinase-like proteins (CLPs) are associated with tissue-remodeling and
inflammation but also with several disorders, including fibrosis, atherosclerosis, allergies …