Polarity-driven two-photon fluorescent probe for monitoring the perturbation in lipid droplet levels during mitochondrial dysfunction and acute pancreatitis

S Biswas, M Baruah, A Shil, S Sarkar, M Ali… - ACS …, 2023 - ACS Publications
Lipid droplets (LDs) act as an energy reservoir in cancer cells; on the other hand,
mitochondria are hyperactive to fulfill the energy demand to accelerate cell proliferation. We …

9-Phenanthrenylvinyl-4′-pyridine and Its N-Methylated Analogue: From the Crystal Structure and Photoisomerization to Photophysical and Electrochemical …

TS Kannan, R Yadav, M Rukmini Sarma… - Crystal Growth & …, 2024 - ACS Publications
Designing novel functional compounds is a key step in coordination and organic materials
chemistry. Herein, 9-phenanthrenylvinyl-4′-pyridine (9-PheVP), as a new ligand, has been …

A Systematic Design and Synthesis of PET‐based Fluorescent Probes for Monitoring pH During Mitophagy

R Yadav, S Munan, M Ali, K Mapa… - Chemistry–An Asian …, 2023 - Wiley Online Library
Mitochondria are the powerhouse of the cell and function at pH∼ 8.0. Dysfunctions of
mitochondria, includes mitochondrial damage, leading to pH alteration. Hence, researchers …

3-Thioxo-3H-indolizinium-1-olates and Related Pseudo-Cross-Conjugated Heterocyclic Mesomeric Betaines: Synthesis and Spectral Features

IV Nechaev, GV Cherkaev - The Journal of Organic Chemistry, 2024 - ACS Publications
The first example of the synthesis of 3-thioxo-3 H-indolizinium-1-olates, which further
expands a limited class of pseudocross-conjugated heterocyclic mesomeric betaines …

A fluorescence probe for imaging lipid droplet and visualization of diabetes-related polarity variations

Z Chen, L Yue, Y Guo, H Huang, W Lin - Analytica Chimica Acta, 2024 - Elsevier
Diabetes mellitus is a disorder that affects lipid metabolism. Abnormalities in the lipid
droplets (LDs) can lead to disturbances in lipid metabolism, which is a significant feature of …

Polarity-Sensitive fluorescent probes based on triphenylamine for fluorescence lifetime imaging of lipid droplets

Q Wang, D Li, Z Zhang, L Shen, H Xu, Z Wang… - … Acta Part A: Molecular …, 2025 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a disease closely associated with metabolic
abnormalities. Lipid droplets (LDs) serve as organelles that store intracellular neutral lipids …

Substituent-regulated photophysical properties of 8a-methyl-2, 3-diphenylindolizin-1 (8aH)-one derivatives and their application in the detection of bilirubin in blood …

L Chakkumkumarath, SS Kanneth… - New Journal of …, 2025 - pubs.rsc.org
8a-methyl-2, 3-diphenylindolizin-1 (8aH)-one derivatives with electronically diverse
substituents at the para position of the C-2 and C-3 phenyl rings were synthesized, and their …