DA Santana, MAC Smith, ES Chen - Genes, 2023 - mdpi.com
Since Late-onset Alzheimer's disease (LOAD) derives from a combination of genetic variants and environmental factors, epigenetic modifications have been predicted to play a role in the …
R Taliyan, V Kakoty, KC Sarathlal… - Journal of Controlled …, 2022 - Elsevier
For the past several years, dementia, is one of the predominantly observed groups of symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …
L Vasileva, G Gaynanova, F Valeeva… - International Journal of …, 2023 - mdpi.com
Liposomes modified with tetradecyltriphenylphosphonium bromide with dual loading of α- tocopherol and donepezil hydrochloride were successfully designed for intranasal …
Experiments have demonstrated that frankincense may offer protection against scopolamine- induced Alzheimer's disease by mitigating cholinergic dysfunction and inhibiting …
In metabolic syndrome, dysregulated signalling activity of the insulin receptor pathway in the brain due to persistent insulin resistance (IR) condition in the periphery may lead to brain IR …
A Tsoy, B Umbayev, A Kassenova… - International journal of …, 2024 - mdpi.com
Although Alzheimer's disease (AD) is traditionally viewed as a central nervous system disorder driven by the cerebral accumulation of toxic beta-amyloid (Aβ) peptide, new …
Alzheimer's Disease (AD) is an irreversible neurodegenerative disease for which no modifying therapies are presently available. Besides the identification of pathological …
ML Nelson, JA Pfeifer, JP Hickey, AE Collins… - Biology, 2023 - mdpi.com
Simple Summary This review focuses on rosiglitazone, a medication used to treat diabetes. Rosiglitazone lowers blood sugar levels by helping the body use insulin more efficiently …
Objective The aim of the current study was to investigate the beneficial effects of rosiglitazone (Rosi) on amyloid beta (Aβ) and glial fibrillary acidic protein (GFAP) in the …