Histone modifications in epigenetic regulation of cancer: Perspectives and achieved progress

ME Neganova, SG Klochkov, YR Aleksandrova… - Seminars in Cancer …, 2022 - Elsevier
Epigenetic changes associated with histone modifications play an important role in the
emergence and maintenance of the phenotype of various cancer types. In contrast to direct …

Goat DNMT3B: An indel mutation detection, association analysis with litter size and mRNA expression in gonads

Y Hui, Y Zhang, K Wang, C Pan, H Chen, L Qu, X Song… - Theriogenology, 2020 - Elsevier
Abstract DNA methyltransferase 3β (DNMT3B) is a gene encoding a de novo methylation
enzyme that is required for DNA methylation during mammalian embryo development …

Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis

J Yoo, GW Kim, YH Jeon, JY Kim, SW Lee… - … & Molecular Medicine, 2022 - nature.com
Distinct epigenetic modifiers ensure coordinated control over genes that govern a myriad of
cellular processes. Growing evidence shows that dynamic regulation of histone methylation …

Pig SOX9: Expression profiles of Sertoli cell (SCs) and a functional 18 bp indel affecting testis weight

M Chen, J Wang, N Liu, W Cui, W Dong, B Xing, C Pan - Theriogenology, 2019 - Elsevier
Sex determining region Y-box 9 (SOX9), an important member of the SRY-type HMGbox
(SOX) gene family, plays an important role in the regulation of mammalian reproduction …

Goat SPEF2: Expression profile, indel variants identification and association analysis with litter size

M Chen, H Yan, K Wang, Y Cui, R Chen, J Liu, H Zhu… - Theriogenology, 2019 - Elsevier
Abstract SPEF2 (sperm flagella 2 gene), also known as KPL2, plays important roles in germ
cell development. The aim of this study was to investigate the mRNA expression profiles of …

Effects of Genetic Variation of the Sorting Nexin 29 (SNX29) Gene on Growth Traits of Xiangdong Black Goat

Y Chen, L Yang, X Lin, P Peng, W Shen, S Tang, X Lan… - Animals, 2022 - mdpi.com
Simple Summary With the development of goat industry, the improvement of goat production
performance has become the primary task of goat industry. Studies have shown that SNX29 …

Goat CTNNB1: mRNA expression profile of alternative splicing in testis and association analysis with litter size

X Zhang, H Yan, K Wang, T Zhou, M Chen, H Zhu… - Gene, 2018 - Elsevier
Abstract Catenin beta 1 (CTNNB1, also known as β-catenin), is a key gene involved in wnt-β-
catenin signaling pathway and plays a significant role in animal reproduction. The aim of this …

Cytoskeleton structure in mouse sperm and testes after 30 days of hindlimb unloading and 12 hours of recovery

MA Usik, IV Ogneva - Cellular Physiology and Biochemistry, 2018 - karger.com
Abstract Background/Aims: Changes in the external mechanical field result in cytoskeleton
reorganization and the formation of adaptive patterns in different types of cells, including …

Research update and opportunity of non-hormonal male contraception: histone demethylase KDM5B-based targeting

S Arifuzzaman, MS Rahman, MG Pang - Pharmacological research, 2019 - Elsevier
With the continued increase in global human population, diverse contraception approaches
have become increasingly essential, including non-hormonal male contraception. Non …

Pig StAR: mRNA expression and alternative splicing in testis and Leydig cells, and association analyses with testicular morphology traits

Y Zhang, Y Cui, X Zhang, Y Wang, J Gao, T Yu, X Lv… - Theriogenology, 2018 - Elsevier
Steroidogenic acute regulatory protein (StAR), primarily expressed in Leydig cells (LCs) in
the mammalian testes, is essential for testosterone biosynthesis and male fertility. However …