[HTML][HTML] The role of silver nanoparticles in the diagnosis and treatment of cancer: Are there any perspectives for the future?

P Takáč, R Michalková, M Čižmáriková, Z Bedlovičová… - Life, 2023 - mdpi.com
Cancer is a fatal disease with a complex pathophysiology. Lack of specificity and
cytotoxicity, as well as the multidrug resistance of traditional cancer chemotherapy, are the …

[HTML][HTML] Traditional ancient Egyptian medicine: A review

AM Metwaly, MM Ghoneim, IH Eissa… - Saudi journal of …, 2021 - Elsevier
The ancient Egyptians practiced medicine with highly professional methods. They had
advanced knowledge of anatomy and surgery. Also, they treated a lot of diseases including …

[HTML][HTML] Multi-step in silico discovery of natural drugs against COVID-19 targeting main protease

EB Elkaeed, FS Youssef, IH Eissa, H Elkady… - International Journal of …, 2022 - mdpi.com
In continuation of our antecedent work against COVID-19, three natural compounds, namely,
Luteoside C (130), Kahalalide E (184), and Streptovaricin B (278) were determined as the …

[HTML][HTML] A multistage in silico study of natural potential inhibitors targeting SARS-CoV-2 main protease

EB Elkaeed, IH Eissa, H Elkady, A Abdelalim… - International Journal of …, 2022 - mdpi.com
Among a group of 310 natural antiviral natural metabolites, our team identified three
compounds as the most potent natural inhibitors against the SARS-CoV-2 main protease …

[HTML][HTML] In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10

IH Eissa, MM Khalifa, EB Elkaeed, EE Hafez… - Molecules, 2021 - mdpi.com
In continuation of our previous effort, different in silico selection methods were applied to
310 naturally isolated metabolites that exhibited antiviral potentialities before. The applied …

[HTML][HTML] In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (Mpro)

MS Alesawy, AE Abdallah, MS Taghour, EB Elkaeed… - Molecules, 2021 - mdpi.com
The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the “COVID-
19” disease that has been declared by WHO as a global emergency. The pandemic, which …

Biogenic silver, gold and copper nanoparticles-A sustainable green chemistry approach for cancer therapy

P Vaid, P Raizada, AK Saini, RV Saini - Sustainable Chemistry and …, 2020 - Elsevier
The advent of nanotechnology has revolutionized the way clinicians are treating cancers.
Treatment for cancer includes surgery, radiotherapy, hormonal therapy, chemotherapy, and …

[HTML][HTML] In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular …

MS Alesawy, EB Elkaeed, AA Alsfouk, AM Metwaly… - Molecules, 2021 - mdpi.com
Papain-like protease is an essential enzyme in the proteolytic processing required for the
replication of SARS-CoV-2. Accordingly, such an enzyme is an important target for the …

[HTML][HTML] Green synthesis of novel stable biogenic gold nanoparticles for breast cancer therapeutics via the induction of extrinsic and intrinsic pathways

NM El-Deeb, SM Khattab, MA Abu-Youssef… - Scientific Reports, 2022 - nature.com
Biosynthesis of gold nanoparticles (AuNPs) using algal polysaccharides is a simple, low-
cost, and an eco-friendly approach. In the current study, different concentrations of …

[HTML][HTML] The Computational Preventive Potential of the Rare Flavonoid, Patuletin, Isolated from Tagetes patula, against SARS-CoV-2

AM Metwaly, EB Elkaeed, BA Alsfouk, AM Saleh… - Plants, 2022 - mdpi.com
The rare flavonoid, patuletin, was isolated from the flowers of Tagetes patula growing in
Egypt. The rarity of the isolated compound inspired us to scrutinize its preventive effect …