Aging is a major cause of many degenerative diseases. The most intuitive consequence of
aging is mainly manifested on the skin, resulting in cumulative changes in skin structure …

Coffee waste is often viewed as a problem, but it can be converted into value-added
products if managed with clean technologies and long-term waste management strategies …

Loss of proteostasis is a fundamental process driving aging. Proteostasis is affected by the
accuracy of translation, yet the physiological consequence of having fewer protein synthesis …

Protein phosphorylation is a post-translational modification (PTM) that orchestrates a diverse
array of cellular processes. Because this modification serves as a rapid and reversible …

Coffee can be an ally in the fight against diseases such as type 2 diabetes, cancer, hepatic
injury, cirrhosis, depression, suicidal behavior, and neurological and cardiovascular …

Skin cells are vulnerable to oxidative stress-induced senescence, which may lead to
abnormal aging or aging-related disorders. Therefore, strategies that can ameliorate …

Ageing is a complex trait controlled by genes and the environment. The highly conserved
mechanistic target of rapamycin signalling pathway (mTOR) is a major regulator of lifespan …

DNA double-strand break (DSB) repair is a highly regulated process performed
predominantly by non-homologous end joining (NHEJ) or homologous recombination (HR) …

Abstract SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-
mediated Evolution) is a genome restructuring technique that can be used in synthetic …

The misfolding, aggregation, and tissue accumulation of proteins are common events in
diverse chronic diseases, known as protein misfolding disorders. Many of these diseases …