Background: Intra-articular (IA) corticosteroid therapy has been used for the treatment of
inflammation and pain in the knee since the 1950s. Purpose: To review the current literature …

Objective To review the current literature on the effects of intraarticular local anesthetics on
human knee articular cartilage. Literature Survey PubMed; MEDLINE; SCOPUS; PEDro; …

BACKGROUND: Intraarticular injections of local anesthetics are frequently used as part of
multimodal pain regimens. However, recent data suggest that local anesthetics affect …

The purpose of this scoping review was to identify possible chondrotoxic effects caused by
drugs usually used for intra-articular injections. PubMed, Scopus, Web of Science and …

Purpose Corticosteroids are commonly injected into the joint space. However, studies have
not examined the chondrotoxicity of one-time injection doses. The purpose of this study is to …

The translational potential of analgesic approaches emerging from basic research can be
augmented by client-owned dog trials. We report on a peripheral interventional approach …

Background Opioid analgesics have been a standard modality for postoperative pain
management after total knee arthroplasty (TKA) but are also associated with increased risk …

Background: Glenohumeral chondrolysis is the irreversible destruction of previously normal
articular cartilage, occurring most commonly after shoulder surgery in young individuals. The …

Purpose Aim of this systematic review of preclinical evidence was to determine the effects of
intra‐articular corticosteroid (CS) injections in joints affected by osteoarthritis (OA). Methods …

Purpose The purpose of this study was to investigate the cytotoxic potency of local
anesthetics on human mesenchymal stem cells (MSCs) before and after chondrogenic …