Heading the list of the critical health-related issues worldwide, cancer continues to be a one
of the most serious life-threatening diseases. The rate of cancer-related mortality is at …

Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

A series of new coumarin based thiazoles were synthesized by the microwave irradiation of
thiocarbohydrazide, aldehydes and 3-(2-bromoacetyl) coumarins. Structures of all the …

Current treatments for gynecological cancers include surgery, radiotherapy, and
chemotherapy. However, these treatments often have significant side effects …

Aim: This research aims to expand the established pharmacological space of tumor-
associated carbonic anhydrases (TACAs) by exploring the synthetically accessible chemical …

An efficient one-pot synthesis of alkyl 4-oxo-coumarinyl ethylidene hydrazono-thiazolidin-5-
ylidene acetate derivatives has successfully been achieved via a three component …

A series of triphenyl substituted pyrimidines as analogous of colchicine and combretastatin
A-4 was synthesized and evaluated for the antiproliferative potential. The compounds were …

Coumarin derivatives occur widely in nature and are a part of both traditional and modern
advancements in synthesis and application. To date, thousands of coumarin derivatives …

Breast cancer is the most common cancer among women. Currently, it poses a significant
threat to the healthcare system due to the emerging resistance and toxicity of available drug …