Combination of stem cells and rehabilitation therapies for ischemic stroke

R Berlet, S Anthony, B Brooks, ZJ Wang… - Biomolecules, 2021 - mdpi.com
Stem cell transplantation with rehabilitation therapy presents an effective stroke treatment.
Here, we discuss current breakthroughs in stem cell research along with rehabilitation …

HMGB1, an evolving pleiotropic protein critical for cellular and tissue homeostasis: role in aging and age-related diseases

E Ruggieri, E Di Domenico, AG Locatelli, F Isopo… - Ageing Research …, 2024 - Elsevier
Aging is a universal biological process characterized by a progressive, cumulative decline in
homeostatic capabilities and physiological functions, which inevitably increases vulnerability …

Histotripsy ablation alters the tumor microenvironment and promotes immune system activation in a subcutaneous model of pancreatic cancer

A Hendricks-Wenger, J Sereno… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
Pancreatic cancer is a significant cause of cancer-related deaths in the United States with an
abysmal five-year overall survival rate that is under 9%. Reasons for this mortality include …

High-CBD extract (CBD-X) downregulates cytokine storm systemically and locally in inflamed lungs

M Aswad, H Hamza, A Pechkovsky, A Zikrach… - Frontiers in …, 2022 - frontiersin.org
Cytokine storm refers to the dysregulated production of inflammatory mediators leading to
hyperinflammation. They are often detrimental, and worsen the severity of COVID-19 and …

[HTML][HTML] HMGB1 in depression: An overview of microglial HMBG1 in the pathogenesis of depression

X Huang, B Wang, J Yang, YJ Lian, HZ Yu… - Brain, Behavior, & …, 2023 - Elsevier
Depression is a prevalent psychiatric disorder with elusive pathogenesis. Studies have
proposed that enhancement and persistence of aseptic inflammation in the central nervous …

Wnt3a loaded deformable hydrogel acts as a 3D culture platform for in situ recruitment of stem cells to efficiently repair bone defects via the asymmetric division

Z Peng, S Niu, L Gui, X Kuang, F Li, B Chen… - Chemical Engineering …, 2022 - Elsevier
Biomaterial-based tissue engineering has emerged as a hotspot in the field of
osteanagenesis. Due to invasive operation in the transplantation process always bring …

Biohybrid nano-platforms manifesting effective cancer therapy: Fabrication, characterization, challenges and clinical perspective

M Aalhate, S Mahajan, A Dhuri, PK Singh - Advances in Colloid and …, 2024 - Elsevier
Nanotechnology-based delivery systems have brought a paradigm shift in the management
of cancer. However, the main obstacles to nanocarrier-based delivery are their limited …

Synergistic effect of Hypoxic Conditioning and Cell‐Tethering Colloidal Gels enhanced Productivity of MSC Paracrine Factors and Accelerated Vessel Regeneration

MC Lee, JS Lee, S Kim, A Jamaiyar, W Wu… - Advanced …, 2024 - Wiley Online Library
Microporous hydrogels have been widely used for delivering therapeutic cells. However,
several critical issues, such as the lack of control over the harsh environment they are …

[HTML][HTML] The role of HMGB1 in digestive cancer

X Chen, Q Liu, E Wu, Z Ma, B Tuo, S Terai, T Li… - Biomedicine & …, 2023 - Elsevier
High mobility group box protein B1 (HMGB1) belongs to the HMG family, is widely
expressed in the nucleus of digestive mucosal epithelial cells, mesenchymal cells and …

Beyond defence: Immune architects of ovarian health and disease

MV Bazzano, A Köninger, ME Solano - Seminars in Immunopathology, 2024 - Springer
Throughout the individual's reproductive period of life the ovary undergoes continues
changes, including cyclic processes of cell death, tissue regeneration, proliferation, and …