Pluripotent stem cell-based cardiac regenerative therapy for heart failure

Y Soma, H Tani, Y Morita-Umei, Y Kishino… - Journal of Molecular and …, 2024 - Elsevier
Cardiac regenerative therapy using human pluripotent stem cell-derived cardiomyocytes
(hPSC-CMs) is expected to become an alternative to heart transplantation for severe heart …

Manipulating and studying gene function in human pluripotent stem cell models

E Balmas, F Sozza, S Bottini, ML Ratto, G Savorè… - FEBS …, 2023 - Wiley Online Library
Human pluripotent stem cells (hPSCs) are uniquely suited to study human development and
disease and promise to revolutionize regenerative medicine. These applications rely on …

Environmental and genetic influence of circadian rhythm over cardiac metabolism and disease

M Orlowska - 2024 - eprints.qut.edu.au
This thesis investigates the impact of physiological and environmental factors on cardiac
health and injury using human cardiac organoids as a model. In this project, a bioreactor …