Secondary metabolites from Rubiaceae species

D Martins, CV Nunez - Molecules, 2015 - mdpi.com
This study describes some characteristics of the Rubiaceae family pertaining to the
occurrence and distribution of secondary metabolites in the main genera of this family. It …

Overview of antifungal drugs against paracoccidioidomycosis: how do we start, where are we, and where are we going?

L do Carmo Silva, AA de Oliveira, DR de Souza… - Journal of Fungi, 2020 - mdpi.com
Paracoccidioidomycosis is a neglected disease that causes economic and social impacts,
mainly affecting people of certain social segments, such as rural workers. The limitations of …

Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes

N Şahin, E Üstün, U Tutar, C Celik, N Gürbüz… - Journal of …, 2021 - Elsevier
In this study, we reported the synthesis of a new series of Silver (I)-N-heterocyclic carbene
complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) …

Synthesis of tetrahydro-β-carbolines, β-carbolines, and natural products,(±)-harmicine, eudistomin U and canthine by reductive Pictet Spengler cyclization

DS Pakhare, RS Kusurkar - Tetrahedron Letters, 2015 - Elsevier
Abstract Reductive Pictet Spengler cyclization was used for the synthesis of naturally
occurring β-carbolines, eudistomin U, and canthine. Other biologically important β …

β-Carboline-1-propionic acid alkaloid: antileishmanial and cytotoxic effects

RS Gabriel, ACF Amaral, IC Lima, JD Cruz… - Revista Brasileira de …, 2019 - SciELO Brasil
Pentavalent antimonials and amphotericin B remain as the main drugs to treat human
leishmaniasis. However, the high toxicity and variable efficacy of treatment have stimulated …

CuBr2-Catalyzed Mild Oxidation of 3,4-Dihydro-β-Carbolines and Application in Total Synthesis of 6-Hydroxymetatacarboline D

TZ Meng, J Zheng, TH Trieu, B Zheng, JJ Wu… - ACS …, 2018 - ACS Publications
A green chemical method for the conversion of 3, 4-dihydro-β-carbolines to β-carbolines has
been developed using air as the oxidant. With 15 mol% CuBr2 as the catalyst, 3, 4-dihydro-β …

Setting new routes for antifungal drug discovery against pathogenic fungi

KS Freitas e Silva, LC Silva… - Current …, 2020 - ingentaconnect.com
Fungal diseases are life-threatening to human health and responsible for millions of deaths
around the world. Fungal pathogens lead to a high number of morbidity and mortality …

One Century of Study: What We Learned about Paracoccidioides and How This Pathogen Contributed to Advances in Antifungal Therapy

E Seki Kioshima, P de Souza Bonfim de Mendonça… - Journal of Fungi, 2021 - mdpi.com
Paracoccidioidomycosis (PCM) is a notable fungal infection restricted to Latin America.
Since the first description of the disease by Lutz up to the present day, Brazilian researchers …

[PDF][PDF] One Century of Study: What We Learned about Paracoccidioides and How This Pathogen Contributed to Advances in Antifungal Therapy. J. Fungi 2021, 7, 106

E Seki Kioshima, P de Souza Bonfim de Mendonca… - 2021 - pdfs.semanticscholar.org
Paracoccidioidomycosis (PCM) is a notable fungal infection restricted to Latin America.
Since the first description of the disease by Lutz up to the present day, Brazilian researchers …

11 Natural Products Structures and Analysis of the Cerrado Flora in Goiás

L Katoa, VGP Severinoa, AM Telesb… - Brazilian Medicinal …, 2019 - api.taylorfrancis.com
The Cerrado is the second largest biome of South America, occupying more than 20% of the
Brazilian territory (MMA, 2018). In terms of area, only the vegetation formation in Brazil of the …