[HTML][HTML] Antimicrobial peptides: an emerging category of therapeutic agents

M Mahlapuu, J Håkansson, L Ringstad… - Frontiers in cellular and …, 2016 - frontiersin.org
Antimicrobial peptides (AMPs), also known as host defense peptides, are short and
generally positively charged peptides found in a wide variety of life forms from …

Tendon functional extracellular matrix

HRC Screen, DE Berk, KE Kadler… - Journal of …, 2015 - Wiley Online Library
This article is one of a series, summarizing views expressed at the Orthopaedic Research
Society New Frontiers in Tendon Research Conference. This particular article reviews the …

Extracellular matrix at the muscle–tendon interface: functional roles, techniques to explore and implications for regenerative medicine

N Narayanan, S Calve - Connective tissue research, 2021 - Taylor & Francis
The muscle-tendon interface is an anatomically specialized region that is involved in the
efficient transmission of force from muscle to tendon. Due to constant exposure to loading …

Functionally distinct tendons from elastin haploinsufficient mice exhibit mild stiffening and tendon-specific structural alteration

JD Eekhoff, F Fang, LG Kahan… - Journal of …, 2017 - asmedigitalcollection.asme.org
Elastic fibers are present in low quantities in tendon, where they are located both within
fascicles near tenocytes and more broadly in the interfascicular matrix (IFM). While elastic …

Experimental evaluation of multiscale tendon mechanics

F Fang, SP Lake - Journal of Orthopaedic Research, 2017 - Wiley Online Library
Tendon's primary function is a mechanical link between muscle and bone. The hierarchical
structure of tendon and specific compositional constituents are believed to be critical for …

Advancements and challenges in bionic joint lubrication biomaterials for sports medicine

L Xiang, Z Wang, W Cui - Biosurface and Biotribology, 2024 - Wiley Online Library
Bionic lubricant materials are a class of materials inspired by natural organisms and offer
excellent lubrication properties and biocompatibility. In the field of sports medicine, their …

[HTML][HTML] Using Load to Improve Tendon/Ligament Tissue Engineering and Develop Novel Treatments for Tendinopathy

KT Tam, K Baar - Matrix Biology, 2024 - Elsevier
Tendon and ligament injuries are highly prevalent but heal poorly, even with proper care.
Restoration of native tissue function is complicated by the fact that these tissues vary …

Cell and biologic-based treatment of flexor tendon injuries

SW Linderman, RH Gelberman, S Thomopoulos… - Operative techniques in …, 2016 - Elsevier
The 2 primary factors leading to poor clinical results after intrasynovial tendon repair are
adhesion formation within the digital sheath and repair-site elongation and rupture. As the …

PXL01 in sodium hyaluronate results in increased PRG4 expression: a potential mechanism for anti-adhesion

S Edsfeldt, B Holm, M Mahlapuu, C Reno… - Upsala Journal of …, 2017 - Taylor & Francis
Purpose: To investigate the anti-adhesive mechanisms of PXL01 in sodium hyaluronate
(HA) by using the rabbit lactoferrin peptide, rabPXL01 in HA, in a rabbit model of healing …

Collagen V deficiency during murine tendon healing results in distinct healing outcomes based on knockdown severity

RJ Leiphart, SN Weiss, MS DiStefano, AA Mavridis… - Journal of …, 2022 - Elsevier
Tendon function is dependent on proper organization and maintenance of the collagen I
tissue matrix. Collagen V is a critical regulator of collagen I fibrils, and while prior studies …