miRNA therapeutics: a new class of drugs with potential therapeutic applications in the heart
BC Bernardo, JYY Ooi, RCY Lin… - Future medicinal …, 2015 - Taylor & Francis
miRNAs are small non-coding RNAs (ncRNAs), which regulate gene expression. Here, the
authors describe the contribution of miRNAs to cardiac biology and disease. They discuss …
authors describe the contribution of miRNAs to cardiac biology and disease. They discuss …
Carbon nanotubes-based electrochemical (bio) sensors for biomarkers
This review is focused on the critical discussion about the most representative carbon
nanotubes (CNTs)-based electrochemical (bio) sensors for the quantification of different …
nanotubes (CNTs)-based electrochemical (bio) sensors for the quantification of different …
The role of microRNAs in acute respiratory distress syndrome and sepsis, from targets to therapies: a narrative review
Acute respiratory distress syndrome (ARDS) is a significant cause of morbidity and mortality
in the intensive care unit (ICU) and is characterized by lung epithelial and endothelial cell …
in the intensive care unit (ICU) and is characterized by lung epithelial and endothelial cell …
Small molecules with big roles in microRNA chemical biology and microRNA-targeted therapeutics
R Fan, C Xiao, X Wan, W Cha, Y Miao, Y Zhou… - RNA biology, 2019 - Taylor & Francis
MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene
expression. Aberrant miRNA expression or function have close links with various human …
expression. Aberrant miRNA expression or function have close links with various human …
[HTML][HTML] MicroRNA-101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma
T Tian, M Mingyi, X Qiu, Y Qiu - Oncotarget, 2016 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is a chemotherapy-resistant brain tumor with limited
treatment options. Temozolomide (TMZ), an alkylating agent, is a front-line …
treatment options. Temozolomide (TMZ), an alkylating agent, is a front-line …
Regulating miRNA-21 biogenesis by bifunctional small molecules
We report a new strategy to regulate microRNAs (miRNAs) biogenesis by using bifunctional
small molecules that consist of a pre-miRNA binding unit connected by a linker to a Dicer …
small molecules that consist of a pre-miRNA binding unit connected by a linker to a Dicer …
Oncogenic microRNAs biogenesis as a drug target: structure–activity relationship studies on new aminoglycoside conjugates
MicroRNAs (miRNAs) are a recently discovered category of small RNA molecules that
regulate gene expression at the post‐transcriptional level. Accumulating evidence indicates …
regulate gene expression at the post‐transcriptional level. Accumulating evidence indicates …
Building of neomycin–nucleobase–amino acid conjugates for the inhibition of oncogenic miRNAs biogenesis
MicroRNAs (miRNAs) are a recently discovered category of small RNA molecules that
regulate gene expression at the post-transcriptional level. Accumulating evidence indicates …
regulate gene expression at the post-transcriptional level. Accumulating evidence indicates …
HDL and microRNA therapeutics in cardiovascular disease
DL Michell, KC Vickers - Pharmacology & therapeutics, 2016 - Elsevier
Abstract microRNAs (miRNA) are small non-coding RNAs (sRNA) that post-transcriptionally
regulate gene (mRNA) expression and are implicated in many biological processes and …
regulate gene (mRNA) expression and are implicated in many biological processes and …
Computational resources for prediction and analysis of functional miRNA and their targetome
Abstract microRNAs are evolutionarily conserved, endogenously produced, noncoding
RNAs (ncRNAs) of approximately 19–24 nucleotides (nts) in length known to exhibit gene …
RNAs (ncRNAs) of approximately 19–24 nucleotides (nts) in length known to exhibit gene …