A Platelet Reactivity ExpreSsion Score derived from patients with peripheral artery disease predicts cardiovascular risk

JS Berger, MG Cornwell, Y Xia, MA Muller… - Nature …, 2024 - nature.com
Platelets are key mediators of atherothrombosis, yet, limited tools exist to identify individuals
with a hyperreactive platelet phenotype. In this study, we investigate the association of …

Inhibiting the P2Y12 Receptor in Megakaryocytes and Platelets Suppresses Interferon-Associated Responses

MA Sowa, H Sun, TT Wang, VW Virginio… - Basic to Translational …, 2024 - jacc.org
The authors investigated the impact of antiplatelet therapy on the megakaryocyte (MK) and
platelet transcriptome. RNA-sequencing was performed on MKs treated with aspirin or …