NK cells are the major lymphocyte subset of the innate immune system that mediates antiviral and anti-tumor responses. It is well established that they develop mechanisms to …
L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their unique biological properties and self-powered functions, such as excellent biocompatibility …
J Qi, F Jin, Y You, Y Du, D Liu, X Xu, J Wang… - Nature …, 2021 - nature.com
Some specific chemotherapeutic drugs are able to enhance tumor immunogenicity and facilitate antitumor immunity by inducing immunogenic cell death (ICD). However, tumor …
H Pan, M Zheng, A Ma, L Liu, L Cai - Advanced Materials, 2021 - Wiley Online Library
Numerous clinical trials for cancer precision medicine research are limited due to the drug resistance, side effects, and low efficacy. Unsatisfactory outcomes are often caused by …
Cancer immunotherapy involves a cascade of events that ultimately leads to cytotoxic immune cells effectively identifying and destroying cancer cells. Responsive nanomaterials …
W Zhang, M Wang, W Tang, R Wen, S Zhou… - Advanced …, 2018 - Wiley Online Library
Macrophages hold great potential in cancer drug delivery because they can sense chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …
NK Lee, SN Kim, CG Park - Biomaterials Research, 2021 - spj.science.org
Immune cells are attractive targets for therapy as they are direct participants in a variety of diseases. Delivering a therapeutic agent only to cells that act on a disease by distinguishing …
The past decade has witnessed the explosive development of cancer immunotherapies. Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target …
N Thakur, S Thakur, S Chatterjee, J Das… - Frontiers in Chemistry, 2020 - frontiersin.org
Cancer immunotherapy has emerged as a promising strategy for the treatment of many forms of cancer by stimulating body's own immune system. This therapy not only eradicates …