Invasive group A streptococcal infections are uncommon, although serious, infections with
high case fatality rates. Periodic resurgences in invasive group A streptococcal infections in …

Toxic shock syndrome (TSS) is an acute, toxin-mediated illness, like endotoxic shock, and is
characterized by fever, rash, hypotension, multiorgan involvement, and desquamation. TSS …

Objective. To determine the most effective antibiotic treatment for invasive S. pyogenes
infection in humans. Design and setting. We conducted a retrospective review of the …

Objectives. To describe the incidence and clinical features of invasive group A streptococcal
(GAS) disease in children in Ontario and determine the risk of invasive GAS infection …

Objective. Varicella is a common infectious disease, usually benign and self-limited, and
complications are believed to be rare. The purpose of this study was to describe the …

Varicella-zoster virus (VZV) is a human herpesvirus of the subfamily Alphaherpesviridae and
the causative agent of varicella, the result of primary VZV infection of a susceptible host. VZV …

Objective. An increase in the incidence of necrotizing fasciitis (NF) occurring in previously
healthy children with primary varicella was noted in the Washington State area between …

We conducted a case-control study to identify risk factors for invasive group A streptococcal
(GAS) infections, which can be fatal. Case-patients were identified when Streptoccus …

The evaluation of nontoxic-appearing young (ie,< 3 y of age) febrile children is a subject of
considerable debate. The controversy became clearly evident with the simultaneous …

Background. Previous studies of occult bacteremia in febrile children have excluded patients
with recognizable viral syndromes (RVS). There is little information in the literature regarding …