The effect of buffer species on biomolecules and biomolecule-nanoparticle interactions is a
phenomenon that has been either neglected, or not understood. Here, we study the …

Abstract Knowledge of DNA-lipid layer interactions is key for the development of biosensors,
synthetic nanopores, scaffolds, and gene-delivery systems. These interactions are strongly …

The present work focuses on the study of the aggregation and complexing properties of
calixarenes as potential DNA condensation agents for gene delivery. In the current study, 1 …

DNA adopts a number of conformations that can affect its binding to other macromolecules.
The conformations (A, B, Z) can be sequence-and/or solution-dependent. While AT-rich DNA …

G‐quadruplex DNA sequences present in the promoter and telomere regions of the genomic
sequence are considered therapeutic targets for the treatment of cancer. Curcumin, derived …

Lipid nanoparticles (LNPs) are efficient and safe carriers for mRNA vaccines based on
advanced ionizable lipids. It is understood that the pH dependent structural transition of the …

We develop the theory of chemical denaturation of DNA for low and medium denaturation
degrees, including but not limited to 50% denaturation as a reversible first-order reaction …

Triple negative breast cancer (TNBC), which lacks the ER, PR and HER-2 expressions is
accounted for the 25% of all breast cancer related deaths in 2019. PIM1 oncogenes were …

When a charged surface comes in contact with an electrolyte solution, an ion adsorption
layer, often referred to as an electric double layer (EDL), is formed. This structure plays a …

Electrolytes are fundamental constituents of biological fluids where they play the important
function to modulate the interactions between biomacromolecules. Weak electrolytes …