Comparative regenerative mechanisms across different mammalian tissues

SE Iismaa, X Kaidonis, AM Nicks, N Bogush… - NPJ Regenerative …, 2018 - nature.com
Stimulating regeneration of complex tissues and organs after injury to effect complete
structural and functional repair, is an attractive therapeutic option that would revolutionize …

Redox signaling in diabetic wound healing regulates extracellular matrix deposition

B Kunkemoeller, TR Kyriakides - Antioxidants & redox signaling, 2017 - liebertpub.com
Significance: Impaired wound healing is a major complication of diabetes, and can lead to
development of chronic foot ulcers in a significant number of patients. Despite the danger …

l-Cysteine as a reducing/capping/gel-forming agent for the preparation of silver nanoparticle composites with anticancer properties

DV Vishnevetskii, AR Mekhtiev, TV Perevozova… - Soft Matter, 2022 - pubs.rsc.org
The present article reports the in situ preparation of silver nanoparticles (AgNPs)
homogeneously distributed in the gel matrix formed using only L-cysteine (CYS) as a bio …

l-Cysteine/AgNO 2 low molecular weight gelators: self-assembly and suppression of MCF-7 breast cancer cells

DV Vishnevetskii, AR Mekhtiev, TV Perevozova… - Soft Matter, 2020 - pubs.rsc.org
We report a new supramolecular hydrogel based on simple amino acids and silver salt
compounds with low molecular weights. The in situ formation of silver nanoparticles during …

Overexpression of manganese superoxide dismutase mitigates ACL injury-induced muscle atrophy, weakness and oxidative damage

CM Latham, PJ Balawender, NT Thomas… - Free Radical Biology …, 2024 - Elsevier
Oxidative stress has been implicated in the etiology of skeletal muscle weakness following
joint injury. We investigated longitudinal patient muscle samples following knee injury …

N-Acetylcysteine Reverses Anxiety and Oxidative Damage Induced by Unpredictable Chronic Stress in Zebrafish

R Mocelin, M Marcon, S D'ambros, J Mattos… - Molecular …, 2019 - Springer
There is accumulating evidence on the use of N-acetylcysteine (NAC) in the treatment of
patients with neuropsychiatric disorders. As a multi-target drug and a glutathione precursor …

[HTML][HTML] MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for …

GL Bellot, X Dong, A Lahiri, SJ Sebastin… - Redox biology, 2019 - Elsevier
Abstract Negative Pressure Wound Therapy (NPWT), a widely used modality in the
management of surgical and trauma wounds, offers clear benefits over conventional wound …

Oxidized LDL‐dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy

E Sommariva, I Stadiotti, M Casella, V Catto… - EMBO Molecular …, 2021 - embopress.org
Arrhythmogenic cardiomyopathy (ACM) is hallmarked by ventricular fibro‐adipogenic
alterations, contributing to cardiac dysfunctions and arrhythmias. Although genetically …

Antioxidant dressing therapy versus standard wound care in chronic wounds (the REOX study): study protocol for a randomized controlled trial

IM Comino-Sanz, MD López-Franco, B Castro… - Trials, 2020 - Springer
Background A wound that does not heal in the orderly stages of the healing process or does
not heal within 3 months is considered a chronic wound. Wound healing is impaired when …

Withdrawal effects following repeated ethanol exposure are prevented by N-acetylcysteine in zebrafish

R Mocelin, M Marcon, AS da Rosa Araujo… - Progress in Neuro …, 2019 - Elsevier
Alcohol abuse is a highly prevalent condition that substantially contributes to global
morbidity and mortality. Most available pharmacological treatments offer little efficacy as …