Physiological and clinical aspects of bioactive peptides from marine animals

S Chakniramol, A Wierschem, MG Cho, KMI Bashir - Antioxidants, 2022 - mdpi.com
Biological molecules in nutraceuticals and functional foods have proven physiological
properties to treat human chronic diseases. These molecules contribute to applications in …

Animal venoms have potential to treat cancer

B Chatterjee - Current topics in medicinal chemistry, 2018 - ingentaconnect.com
The resistance to chemotherapeutics by the cancerous cells has made its treatment more
complicated. Animal venoms have emerged as an alternative strategy for anti-cancer …

Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell …

CP Silva, TR Costa, RMA Paiva, ACO Cintra… - Journal of Venomous …, 2015 - SciELO Brasil
Abstract Background Phospholipases A 2 (PLA 2 s) are abundant components of snake
venoms that have been extensively studied due to their pharmacological and …

[HTML][HTML] Biological effects of Naja haje crude venom on the hepatic and renal tissues of mice

AA Tohamy, AF Mohamed, AEA Moneim… - Journal of king saud …, 2014 - Elsevier
Snake venoms are known to cause different metabolic disorders, altering cellular and
enzymatic activities in animals and releasing pharmacological substances. In this study, the …

GK-1 induces oxidative stress, mitochondrial dysfunction, decreased membrane potential, and impaired autophagy flux in a mouse model of breast cancer

A Cruz-Gregorio, AK Aranda-Rivera, OE Aparicio-Trejo… - Antioxidants, 2022 - mdpi.com
Breast cancer (BC) is the second most common cancer worldwide in women. During the last
decades, the mortality due to breast cancer has progressively decreased due to early …

Redox state associated with antitumor and immunomodulatory peptides in cancer

A Cruz-Gregorio, AK Aranda-Rivera, E Sciutto… - Archives of Biochemistry …, 2022 - Elsevier
Cancer, a major public health problem, is the fourth cause of death in the world. While
cancer mortality has decreased in recent decades due to more effective treatments, mostly …

[HTML][HTML] Proteomic analysis of the venom of Conus flavidus from Red Sea reveals potential pharmacological applications

MO Germoush, M Fouda, H Aly, I Saber… - Journal of Genetic …, 2024 - Elsevier
Background Venomous marine cone snails produce unique neurotoxins called
conopeptides or conotoxins, which are valuable for research and drug discovery …

Uncovering intense protein diversification in a cone snail venom gland using an integrative venomics approach

D Biass, A Violette, N Hulo, F Lisacek… - Journal of proteome …, 2015 - ACS Publications
Marine cone snail venoms are highly complex mixtures of peptides and proteins. They have
been studied in-depth over the past 3 decades, but the modus operandi of the venomous …

Antiproliferative activity of marine stingray Dasyatis sephenvenom on human cervical carcinoma cell line

RK Rajeshkumar, R Vennila, S Karthikeyan… - Journal of Venomous …, 2015 - SciELO Brasil
Background Venoms comprise mixtures of numerous bioactive compounds that have a wide
range of pharmacologic actions. Toxins from venomous animals have attracted the attention …

[PDF][PDF] Potential inhibition of ehrlich ascites carcinoma by naja nubiae crude venom in swiss albino mice

AS Mohamed, MAM Elkareem… - Biointerface …, 2022 - biointerfaceresearch.com
Cancer, the uncontrolled growth of cells, is a noteworthy cause of death globally. The
present investigation attempted to study the potential efficacy of the Naja nubiae snake …