Krüppel-associated box domain zinc finger proteins (KRAB-ZFPs) are the largest family of
transcriptional regulators in higher vertebrates. Characterized by an N-terminal KRAB …

Almost half of the human genome is made up of transposable elements (TEs), and about 8%
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …

We show that DNA methyltransferase inhibitors (DNMTis) upregulate immune signaling in
cancer through the viral defense pathway. In ovarian cancer (OC), DNMTis trigger cytosolic …

Transposable elements (TEs) are abundant in the human genome, and some are capable of
generating new insertions through RNA intermediates. In cancer, the disruption of cellular …

Recent studies have uncovered myriad viral sequences that are integrated
or'endogenized'in the genomes of various eukaryotes. Surprisingly, it appears that not just …

More than forty per cent of the mammalian genome is derived from retroelements, of which
about one-quarter are endogenous retroviruses (ERVs). Some are still active, notably in …

Transposable elements (TEs) have a unique ability to mobilize to new genomic locations,
and the major advance of second-generation DNA sequencing has provided insights into …

Although viruses are most often studied as pathogens, many are beneficial to their hosts,
providing essential functions in some cases and conditionally beneficial functions in others …

Transposable elements comprise roughly 40% of mammalian genomes. They have an
active role in genetic variation, adaptation and evolution through the duplication or deletion …

This is the 4th edition of a book that was initiated with the annotation of the function of all the
genes in the most commonly studied baculovirus, AcMNPV. It has been almost six years …