During persistent infection and hypoxic-stress, Mycobacterium tuberculosis (Mtb) expresses
a series of Mtb latency antigens. The aim of this study was to evaluate the immunogenicity of …

Understanding functional interactions between DCs and antigens is necessary for achieving
an optimal and desired immune response during vaccine development. Here, we identified …

Molecular chaperones are a set of conserved proteins that have evolved to assist the folding
of many newly synthesized proteins by preventing their misfolding under conditions such as …

A third of the world's population is infected with Mycobacterium tuberculosis, and 2 million
people die from tuberculosis every year. The only tuberculosis vaccine currently available is …

Background Streptomycin (SM) is a broad spectrum antibiotic and is an important
component of any anti-tuberculosis therapy regimen. Several mechanisms have been …

Monocyte migration into tissues, an important event in inflammation, requires an intricate
interplay between determinants on cell surfaces and extracellular matrix (ECM). Galectin‐3 …

ABSTRACT DNA‐based vaccine is a promising candidate for immunization and induction of
a T‐cell‐focused protective immune response against infectious pathogens such as …

A Bacille Calmette–Guérin (BCG) is still the only licensed vaccine for the prevention of
tuberculosis, providing limited protection against Mycobacterium tuberculosis infection in …

During the last decade, the propagation of immunological knowledge describing the critical
role of dendritic cells (DC) in the induction of efficacious immune responses has promoted …

Vaccination is one of the most powerful health tools available owing to its ability to confer
protection against various diseases. The long-term impact of such protection in terms of …