Introduction: Inter-observer variability (IOV) in target volume delineation is a well-
documented source of geometric uncertainty in radiotherapy. Such variability has not yet …

Purpose: To accurately quantify the local difference between two contour surfaces in two‐or
three‐dimensional space, a new, robust point‐to‐surface distance measure is developed …

Purpose To investigate interobserver delineation variability for gross tumor volumes of
primary lung tumors and associated pathologic lymph nodes using magnetic resonance …

Computer technology is widely used for multimodal image analysis of the prostate gland.
Several techniques have been developed, most of which incorporate a priori knowledge …

Purpose: To compare two coverage‐based planning (CP) techniques with fixed margin‐
based (FM) planning for high‐risk prostate cancer treatments, with the exclusive …

Purpose Variability in contouring contributes to large variations in radiation therapy planning
and treatment outcomes. The development and testing of tools to automatically detect …

Intensity-driven image registration does not always produce satisfactory pointwise
correspondences in regions of low soft-tissue contrast characteristic of pelvic computed …

An important research problem in image-guided radiation therapy is how to accurately
register daily onboard Cone-beam CT (CBCT) images to higher quality pretreatment fan …

A fundamental challenge in the treatment planning process of multi-fractional external-beam
radiation therapy (EBRT) is the tradeoff between tumor control and normal tissue sparing in …

Purpose: To illustrate a method for quantifying systematic and random three-dimensional
(3D) segmentation uncertainties for an anatomical structure of arbitrary shape within a …