Mechanistic insights and the clinical prospects of targeted therapies for glioblastoma: a comprehensive review

Y Shen, DKH Thng, ALA Wong, TB Toh - Experimental Hematology & …, 2024 - Springer
Glioblastoma (GBM) is a fatal brain tumour that is traditionally diagnosed based on
histological features. Recent molecular profiling studies have reshaped the World Health …

Lessons from anti–vascular endothelial growth factor and anti–vascular endothelial growth factor receptor trials in patients with glioblastoma

C Lu-Emerson, DG Duda, KE Emblem… - Journal of Clinical …, 2015 - ascopubs.org
Treatment of glioblastoma (GBM), the most common primary malignant brain tumor in adults,
remains a significant unmet need in oncology. Historically, cytotoxic treatments provided …

Incidence and management of olaratumab infusion-related reactions

BA Van Tine, R Govindarajan, S Attia… - Journal of oncology …, 2019 - ascopubs.org
PURPOSE: Olaratumab is a human monoclonal immunoglobulin G1 antibody against
platelet-derived growth factor receptor-α. We report the nature and frequency of infusion …

[PDF][PDF] Characterization of Angiogenesis-Related Molecules in Glioblastoma: potential application as biomarkers for bevacizumab-based therapy

BMF de Carvalho - 2022 - repositorio-aberto.up.pt
Após anos de investigação, o prognóstico do glioblastoma (GBM) permanece ominoso. A
temozolomida (TMZ) associada à radioterapia permitiu alcançar uma sobrevivência global …