The term 'stress'–coined in 1936–has many definitions, but until now has lacked a
theoretical foundation. Here we present an information-theoretic approach–based on the …

Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …

The hippocampus provided the gateway into much of what we have learned about stress
and brain structural and functional plasticity, and this initial focus has expanded to other …

Alzheimer's disease is a progressive loss of memory and cognition, for which there is no
cure. Although genetic studies initially suggested a primary role for amyloid-in Alzheimer's …

The relationship between obesity and cognitive impairment is important given the globally
ageing population in whom cognitive decline and neurodegenerative disorders will carry …

For the last five decades, science has managed to delineate the mechanisms by which
stress hormones can impact on the human brain. Receptors for glucocorticoids are found in …

Approximately 1 in 5 children in the United States lives in poverty, and> 40% of children are
poor or near-poor. 1 In 2013, the American Academy of Pediatrics added child poverty to its …

Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

As the field begins to test the concept of a" preclinical" stage of neurodegenerative disease,
when the pathophysiological process has begun in the brain, but clinical symptoms are not …

The population of aged individuals is increasing worldwide and this has significant health
and socio-economic implications. Clinical and experimental studies on aging have …