mRNA Cancer vaccines: construction and boosting strategies
In late 2020, the US Food and Drug Administration (FDA) approved a lipid-based mRNA
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …
[HTML][HTML] Emerging vaccine nanotechnology: from defense against infection to sniping cancer
Looking retrospectively at the development of humanity, vaccination is an unprecedented
medical landmark that saves lives by harnessing the human immune system. During the …
medical landmark that saves lives by harnessing the human immune system. During the …
Nanobiomaterial-based vaccination immunotherapy of cancer
Cancer immunotherapies including cancer vaccines, immune checkpoint blockade or
chimeric antigen receptor T cells have been exploited as the attractive treatment modalities …
chimeric antigen receptor T cells have been exploited as the attractive treatment modalities …
Nanomedicines inhibiting tumor metastasis and recurrence and their clinical applications
Tumor metastasis and recurrence is one of the biggest problems in curing cancers. Due to
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …
Image-guided intratumoral immunotherapy: Developing a clinically practical technology
Immunotherapy has revolutionized the contemporary oncology landscape, with durable
responses possible across a range of cancer types. However, the majority of cancer patients …
responses possible across a range of cancer types. However, the majority of cancer patients …
[HTML][HTML] Overcoming challenges in the delivery of STING agonists for cancer immunotherapy: a comprehensive review of strategies and future perspectives
C Huang, N Shao, Y Huang, J Chen, D Wang, G Hu… - Materials Today Bio, 2023 - Elsevier
Abstract STING (Stimulator of Interferon Genes) agonists have emerged as promising agents
in the field of cancer immunotherapy, owing to their excellent capacity to activate the innate …
in the field of cancer immunotherapy, owing to their excellent capacity to activate the innate …
Time-programmed delivery of sorafenib and anti-CD47 antibody via a double-layer-gel matrix for postsurgical treatment of breast cancer
L Huang, Y Zhang, Y Li, F Meng, H Li, H Zhang, J Tu… - Nano-Micro Letters, 2021 - Springer
The highly immunosuppressive microenvironment after surgery has a crucial impact on the
recurrence and metastasis in breast cancer patients. Programmable delivery of …
recurrence and metastasis in breast cancer patients. Programmable delivery of …
Cancer vaccines: from the state of the art to the most promising frontiers in the treatment of colorectal cancer
E Martinis, C Ricci, C Trevisan, G Tomadini, S Tonon - Pharmaceutics, 2023 - mdpi.com
Colorectal cancer represents 10% of all new cancer cases each year and accounts for
almost 10% of all cancer deaths. According to the WHO, by 2040 there will be a 60 …
almost 10% of all cancer deaths. According to the WHO, by 2040 there will be a 60 …
Indocyanine green and poly I: C containing thermo-responsive liposomes used in immune-photothermal therapy prevent cancer growth and metastasis
Background Efficient cancer therapy is sought not only for primary tumor treatment but also
for the prevention of metastatic cancer growth. Immunotherapy has been shown to prevent …
for the prevention of metastatic cancer growth. Immunotherapy has been shown to prevent …
Nanotechnology in cervical cancer immunotherapy: Therapeutic vaccines and adoptive cell therapy
X Zhou, H Lian, H Li, M Fan, W Xu, Y Jin - Frontiers in Pharmacology, 2022 - frontiersin.org
Immunotherapy is an emerging method for the treatment of cervical cancer and is more
effective than surgery and radiotherapy, especially for recurrent cervical cancer. However …
effective than surgery and radiotherapy, especially for recurrent cervical cancer. However …