Recent advances in interrogating RNA folding dynamics have shown the classical model of
RNA folding to be incomplete. Here, we pose three prominent questions for the field that are …

Characterizing RNA structures and functions have mostly been focused on 2D, secondary
and 3D, tertiary structures. Recent advances in experimental and computational techniques …

Background Single-stranded nucleic acids (ssNAs) have important biological roles and a
high biotechnological potential linked to their ability to bind to numerous molecular targets …

Regulatory RNA elements fulfill functions such as translational regulation, control of
transcript levels, and regulation of viral genome replication. Trans-acting factors (ie, RNA …

Commensal and pathogenic bacteria continuously evolve to survive in diverse ecological
niches by efficiently coordinating gene expression levels in their ever-changing …

Riboswitches are metabolite-binding RNA regulators that modulate gene expression at the
levels of transcription and translation. One of the hallmarks of riboswitch regulation is that …

Prokaryotic organisms frequently use riboswitches to quantify intracellular metabolite
concentration via high-affinity metabolite receptors. Riboswitches possess a metabolite …

Abstract Human Long Intergenic Noncoding RNA-p21 (LincRNA-p21) is a regulatory
noncoding RNA that plays an important role in promoting apoptosis. LincRNA-p21 is also …

PlzA is ac‐di‐GMP‐binding protein crucial for adaptation of the Lyme disease spirochete
Borrelia (Borreliella) burgdorferi during its enzootic life cycle. Unliganded apo‐PlzA is …

Accurate identification of the correct, biologically relevant RNA structures is critical to
understanding various aspects of RNA biology since proper folding represents the key to …