Isothermal amplifications–a comprehensive review on current methods

J Glökler, TS Lim, J Ida, M Frohme - Critical reviews in biochemistry …, 2021 - Taylor & Francis
The introduction of nucleic acid amplification techniques has revolutionized the field of
medical diagnostics in the last decade. The advent of PCR catalyzed the increasing …

Point-of-care nucleic acid testing for infectious diseases

A Niemz, TM Ferguson, DS Boyle - Trends in biotechnology, 2011 - cell.com
Nucleic acid testing for infectious diseases at the point of care is beginning to enter clinical
practice in developed and developing countries; especially for applications requiring fast …

Point-of-care DNA amplification for disease diagnosis and management

JR Botella - Annual Review of Phytopathology, 2022 - annualreviews.org
Early detection of pests and pathogens is of paramount importance in reducing agricultural
losses. One approach to early detection is point-of-care (POC) diagnostics, which can …

Miniaturized isothermal nucleic acid amplification, a review

PJ Asiello, AJ Baeumner - Lab on a Chip, 2011 - pubs.rsc.org
Micro-Total Analysis Systems (µTAS) for use in on-site rapid detection of DNA or RNA are
increasingly being developed. Here, amplification of the target sequence is key to increasing …

PCR technologies for point of care testing: progress and perspectives

S Petralia, S Conoci - ACS sensors, 2017 - ACS Publications
Since the Human Genome Project completed in 2000, the sequencing of the first genome,
massive progress has been made by medical science in the early diagnosis and …

Real-time detection of isothermal amplification reactions with thermostable catalytic hairpin assembly

Y Jiang, B Li, JN Milligan, S Bhadra… - Journal of the American …, 2013 - ACS Publications
Catalytic hairpin assembly (CHA) is an enzyme-free amplification method that has
previously proven useful in amplifying and transducing signals at the terminus of nucleic …

Interfacing pathogen detection with smartphones for point-of-care applications

X Ding, MG Mauk, K Yin, K Kadimisetty… - Analytical chemistry, 2018 - ACS Publications
Infectious diseases are clinically relevant, transmissible illnesses caused by
microorganisms, such as bacteria, viruses, fungi, and parasites. According to a recent report …

Real-time sequence-validated loop-mediated isothermal amplification assays for detection of Middle East respiratory syndrome coronavirus (MERS-CoV)

S Bhadra, YS Jiang, MR Kumar, RF Johnson… - PloS one, 2015 - journals.plos.org
The Middle East respiratory syndrome coronavirus (MERS-CoV), an emerging human
coronavirus, causes severe acute respiratory illness with a 35% mortality rate. In light of the …

Recent advances of food safety detection by nucleic acid isothermal amplification integrated with CRISPR/Cas

J Qiao, Z Zhao, Y Li, M Lu, S Man, S Ye… - Critical Reviews in …, 2023 - Taylor & Francis
Food safety problems have become one of the most important public health issues
worldwide. Therefore, the development of rapid, effective and robust detection is of great …

Ultrasensitive version of nucleic acid sequence-based amplification (NASBA) utilizing a nicking and extension chain reaction system

Y Ju, HY Kim, JK Ahn, HG Park - Nanoscale, 2021 - pubs.rsc.org
Nucleic acid sequence-based amplification (NASBA) is a transcription-based isothermal
amplification technique especially designed for the detection of RNA targets. The NASBA …