Dmrt genes in the development and evolution of sexual dimorphism

A Kopp - Trends in Genetics, 2012 - cell.com
Most animals are sexually dimorphic, but different taxa have different sex-specific traits.
Despite major differences in the genetic control of sexual development among animal …

Vive la difference: males vs females in flies vs worms

TW Cline, BJ Meyer - Annual review of genetics, 1996 - annualreviews.org
▪ Abstract For 600 million years, the two best-understood metazoan species, the nematode
Caenorhabditis elegans and the fruit fly Drosophila melanogaster, have developed …

Genetic control and evolution of sexually dimorphic characters in Drosophila

A Kopp, I Duncan, SB Carroll - Nature, 2000 - nature.com
Sexually dimorphic abdominal pigmentation and segment morphology evolved recently in
the melanogaster species group of the fruitfly Drosophila. Here we show that these traits are …

The regulation and evolution of a genetic switch controlling sexually dimorphic traits in Drosophila

TM Williams, JE Selegue, T Werner, N Gompel, A Kopp… - Cell, 2008 - cell.com
Sexually dimorphic traits play key roles in animal evolution and behavior. Little is known,
however, about the mechanisms governing their development and evolution. One recently …

Sex and the single cell. II. There is a time and place for sex

CC Robinett, AG Vaughan, JM Knapp, BS Baker - PLoS biology, 2010 - journals.plos.org
The Drosophila melanogaster sex hierarchy controls sexual differentiation of somatic cells
via the activities of the terminal genes in the hierarchy, doublesex (dsx) and fruitless (fru) …

Sex-and tissue-specific functions of Drosophila doublesex transcription factor target genes

E Clough, E Jimenez, YA Kim, C Whitworth… - Developmental cell, 2014 - cell.com
Primary sex-determination" switches" evolve rapidly, but Doublesex (DSX)-related
transcription factors (DMRTs) act downstream of these switches to control sexual …

A homologue of the Drosophila doublesex gene is transcribed into sex-specific mRNA isoforms in the silkworm, Bombyx mori

F Ohbayashi, MG Suzuki, K Mita, K Okano… - … and Physiology Part B …, 2001 - Elsevier
The doublesex (dsx) gene is known as the final gene of the sex-determining cascade in
Drosophila melanogaster. We have isolated a homologue of dsx in the silkworm, Bombyx …

Evolution of Sex-Specific Traits through Changes in HOX-Dependent doublesex Expression

K Tanaka, O Barmina, LE Sanders, MN Arbeitman… - PLoS …, 2011 - journals.plos.org
Almost every animal lineage is characterized by unique sex-specific traits, implying that such
traits are gained and lost frequently in evolution. However, the genetic mechanisms …

Sex comes in from the cold: the integration of sex and pattern

AE Christiansen, EL Keisman, SM Ahmad, BS Baker - Trends in genetics, 2002 - cell.com
There has recently been a revolution in our understanding of how the Drosophila sex-
determination hierarchy generates somatic sexual dimorphism. Most significantly, the sex …

Analysis of the doublesex female protein in Drosophila melanogaster: role in sexual differentiation and behavior and dependence on intersex

JA Waterbury, LL Jackson, P Schedl - Genetics, 1999 - academic.oup.com
Abstract doublesex (dsx) is unusual among the known sex-determination genes of
Drosophila melanogaster in that functional homologs are found in distantly related species …